Zebeta is used for treating patients with high blood pressure. It may be used alone or together with other medications.

How Taken

The usual dose of zebeta is 5 mg or 10 mg once daily although doses up to 20 mg daily have been prescribed. Some patients, for example, those with marked kidney, liver or lung diseases, may be given 2.5 mg daily. Zebeta can be taken with or without food.

Missed Dose

If you miss a dose of this medicine, take it if you remember the same day. If you do not remember until the next day, skip the missed dose. Do not take 2 doses at once.

Storage

Zebeta should be stored at room temperature, 59-86 degrees F (15-30 degrees C) in an air-tight container.

Possible Side Effects

Zebeta is generally well-tolerated, and side effects are mild and transient. Rare side effects include abdominal cramps, diarrhea, dizziness, headache, nausea, impotence, slow heart rate, low blood pressure, numbness, tingling, cold extremities, sore throat, and shortness of breath or wheezing. Zebeta can aggravate breathing difficulties in patients with asthma, chronic bronchitis, or emphysema. In patients with existing slow heart rates (bradycardias) and heart blocks (defects in electrical conduction within the heart), zebeta can cause dangerously slow heart rates and even shock. Zebeta reduces the force of contraction of heart muscle and can aggravate symptoms of heart failure. In patients with coronary artery disease, abruptly stopping zebeta can suddenly worsen angina, and occasionally precipitate heart attacks. If it is necessary to discontinue zebeta, its dosage can be reduced gradually over one to two weeks. Zebeta can mask the early warning symptoms of low blood sugar (hypoglycemia), and should be used with caution in patients receiving treatment for diabetes.

More Information

Do not share this medicine with others for whom it was not prescribed. Do not use this medicine for other health conditions. Keep this medicine out of the reach of children. If using this medicine for an extended period of time, obtain refills before your supply runs out.

Zebeta

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Zetia treats high blood cholesterol along with a low-fat, low-cholesterol diet. It is also used to treat high blood sitosterol and campesterol along with diet therapy.

How Taken

Use Zetia as directed by your doctor.
Take Zetia by mouth with or without food.
Taking Zetia at the same time each day will help you remember to take it.
If you also take a bile acid sequestrant (eg, cholestyramine, colesevelam, colestipol), do not take it within 4 hours before or 2 hours after taking Zetia . Check with your doctor if you have questions.
Continue to use Zetia even if you feel well. Do not miss any doses.
Ask your health care provider any questions you may have about how to use Zetia.

Missed Dose

If you miss a dose of Zetia , take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Storage

Store Zetia at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Zetia out of the reach of children and away from pets.

Possible Side Effects

Check with your doctor if any of these most common side effects persist or become bothersome:
diarrhea; dizziness; headache; joint pain; sinus inflammation; sore throat; stomach pain; tiredness.
Seek medical attention right away if any of these severe side effects occur:

severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); chest pain; dark urine; unexplained muscle pain, tenderness, or weakness; yellowing of the eyes or skin.

More Information

Zetia is to be used only by the patient for whom it is prescribed. Do not share it with other people

Zetia

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This medication is used to help prevent the return of a certain abnormally fast heartbeat (occasional atrial fibrillation) that causes severe symptoms. Propafenone belongs to a class of drugs known as antidysrhythmics. It works by blocking the abnormal electrical activity of an abnormal heartbeat so that the normal heartbeat can occur.

Notes

• Do not share this medication with others.Laboratory and/or medical tests (e.g., EKG, blood mineral tests) should be performed periodically to monitor your progress or check for side effects.
• Consult your doctor for more details.

Storage

• Store at room temperature at 77 degrees F (25 degrees C) away from light and moisture.
• Brief storage between 59-86 degrees F (15-30 degrees C) is permitted.
• Do not store in the bathroom.
• Keep all medicines away from children and pets.

Overdose

• Symptoms of overdose may include: severe dizziness/sleepiness, very slow heartbeat, very fast/irregular heartbeat, fainting.

How To Use

• This medication may be started at a low dose so that your doctor can determine the best dose, increase it gradually as needed, and monitor you closely for side effects.Take this medication by mouth exactly as prescribed by your doctor, with or without food, usually every 12 hours or as directed.
• Do not crush, chew or split the capsules.
• Doing so may increase side effects.Dosage is based on your medical condition, liver function, and response to therapy.This medication works best when the amount of drug in your body is kept at a constant level.
• Therefore, take this drug at evenly spaced intervals.
• To help you remember, take it at the same times each day.Do not take more or less of this drug than prescribed or stop taking it (or other heart medicines) even for a short time unless directed to do so by your doctor.
• Skipping or changing your dose without approval from your doctor may cause your abnormal heartbeat to return.
• It is very important to avoid running out of this medication.
• Therefore, always order your refills several days early.Contact your doctor immediately and seek emergency medical attention (e.g., call -911, have someone else drive you to a hospital emergency room) if your condition persists or worsens.

Side Effects

• See also Warning section.Dizziness, metallic/salty taste in the mouth, nausea/vomiting, constipation, anxiety, tiredness, feeling short of breath, swelling of ankles/legs, and increased infections of the airways (e.g., chest colds) may occur.
• Less common side effects may also include diarrhea, gas, dry mouth, weakness, and blurred vision.
• If any of these effects persist or worsen, tell your doctor or pharmacist promptly.Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects.
• Many people using this medication do not have serious side effects.Tell your doctor immediately if any of these unlikely but serious side effects occur: fainting, persistent abnormally fast heartbeat at rest, short bursts of pounding heartbeat, signs of asthma (e.g., wheezing, persistent/phlegmy cough), worsening symptoms of heart failure (e.g., ankle/leg swelling, increased tiredness, increased shortness of breath when lying down), increased/easy bruising.Tell your doctor immediately if any of these rare but very serious side effects occur: butterfly-shaped facial rash with unusual tiredness and joint/muscle aches, signs of serious infection (e.g., high fever, severe chills, weakness, persistent sore throat), signs of liver problems (e.g., persistent nausea/vomiting, stomach/abdominal pain, yellowing eyes/skin, dark urine, severe tiredness).Propafenone has also rarely caused temporarily decreased sperm counts in men.A very serious allergic reaction to this drug is rare.
• However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching, swelling, severe dizziness, trouble breathing.If you notice other effects not listed above, contact your doctor or pharmacist.

Precautions

• See also Warning section.Before taking propafenone, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies.This medication should not be used if you have certain medical conditions.
• Before using this medicine, consult your doctor or pharmacist if you have: heart failure, certain heartbeat problems (e.g., second- or third-degree atrioventricular block unless you have a heart pacemaker, sick sinus syndrome, bundle branch block), very slow heartbeat, shock due to the heart not pumping well (e.g., very low blood pressure and loss of consciousness), low blood minerals (potassium, magnesium), asthma.Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver problems, kidney problems, previous heart attack, lung problems (e.g., chronic bronchitis, emphysema), myasthenia gravis.Contact your doctor immediately if you develop other illnesses/conditions such as prolonged diarrhea, large quantities of diarrhea, heavy sweating, vomiting, prolonged loss of appetite, prolonged loss of desire to drink water.
• These conditions could cause you to have serious changes in blood minerals, leading to increased side effects from propafenone.This drug may make you dizzy or drowsy.
• Use caution while driving, using machinery, or doing any activity that requires alertness.
• Limit alcoholic beverages.Caution is advised when using this drug in the elderly because they may be more sensitive to the effects of the drug, especially drowsiness/dizziness.During pregnancy, this medication should be used only when clearly needed.
• Discuss the risks and benefits with your doctor.This medication passes into breast milk and may have undesirable effects on a nursing infant.
• Consult your doctor before breast-feeding.

Missed Dose

• If you miss a dose, take it as soon as you remember.
• If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule.
• Do not double the dose to catch up.

Drug Interactions

• Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them.
• Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first.This drug should not be used with the following medications because very serious interactions may occur: disopyramide, amiodarone, quinidine, procainamide, ibutilide, sotalol, moricizine, droperidol, bepridil, dofetilide, cisapride, pimozide, halofantrine, ranolazine, lopinavir/ritonavir, tipranavir, saquinavir.Other drugs besides propafenone and those listed above that may affect the heart rhythm (QTc prolongation in the EKG) include flecainide, tolterodine, mesoridazine, amitriptyline, levofloxacin, and erythromycin, among others.
• QTc prolongation can infrequently result in a serious (rarely fatal) irregular heartbeat.
• Consult your doctor or pharmacist for more details and for instructions on how you may minimize the risk of this effect.If you are currently using any of these medications listed above, tell your doctor or pharmacist before starting propafenone.Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: digoxin, beta blockers (e.g., propranolol, metoprolol), venlafaxine, fluoxetine, desipramine, warfarin, cimetidine, theophylline, rifampin, phenobarbital, cyclosporine, orlistat.

Rythmol SR

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