Zocor is a cholesterol-lowering drug. Your doctor may prescribe Zocor in addition to a cholesterol-lowering diet if your blood cholesterol level is too high, and if you have been unable to lower it by diet alone. For people at high risk of heart disease, current guidelines call for considering drug therapy when LDL levels reach 130. For people at lower risk, the cut-off is 160. For those at little or no risk, it’s 190.

In people with high cholesterol and heart disease, Zocor reduces the risk of heart attack, stroke, and “mini-stroke” (transient ischemic attack) and can stave off the need for bypass surgery or angioplasty to clear clogged arteries. Zocor can also reduce these risks in people with diabetes, peripheral vascular disease, and a history of stroke.

Most important fact about Zocor

Zocor is usually prescribed only if diet, exercise, and weight-loss fail to bring your cholesterol level under control. It’s important to remember that Zocor is a supplement to–not a substitute for–those other measures. To get the full benefit of the medication, you need to stick to the diet and exercise program prescribed by your doctor. All these efforts to keep your cholesterol levels normal are important because together they may lower your risk of heart disease.

How should you take Zocor?

Take Zocor exactly as prescribed.

–If you miss a dose…

Take it as soon as you remember. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Do not take 2 doses at once.

–Storage instructions…

Store at room temperature.

What side effects may occur?

Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine whether it is safe for you to continue taking Zocor.

• More common side effects may include:
  Abdominal pain, headache

Why should Zocor not be prescribed?

Do not take Zocor if you have ever had an allergic reaction to it or are sensitive to it.

Do not take Zocor if you have active liver disease.

Possible food and drug interactions when taking Zocor

Zocor tends to enhance the effects of the blood-thinning drug Coumadin and the heart medication Lanoxin. Combining it with the following drugs increases the chance of muscle damage:

Amiodarone (Cordarone)
Clarithromycin (Biaxin)
Clofibrate (Atromid-S)
Cyclosporine (Sandimmune, Neoral)
Erythromycin (PCE and others)
Fenofibrate (Tricor)
Gemfibrozil (Lopid)
Itraconazole (Sporanox)
Ketoconazole (Nizoral)
Nefazodone (Serzone)
Nicotinic acid or niacin (Niaspan)
Protease inhibitors (used in the treatment of HIV), including Agenerase, Crixivan, Fortovase, Invirase, Norvir, and Viracept
Verapamil (Calan)

If you are taking Zocor with any of these drugs (or with large quantities of grapefruit juice) alert your doctor immediately at the first sign of muscle pain or weakness. If you need to take erythromycin, Biaxin, Nizoral, or Sporanox, the doctor may temporarily take you off Zocor.

Special information if you are pregnant or breastfeeding

You must not become pregnant while taking Zocor. This drug lowers cholesterol, and cholesterol is needed for a baby to develop properly. If you do become pregnant while taking Zocor, notify your doctor right away. Based on studies of other cholesterol-lowering drugs, it is assumed that Zocor could appear in breast milk and could cause severe adverse effects in a nursing baby. Do not take Zocor while breastfeeding your baby.

Recommended dosage

You will have to follow a standard cholesterol-lowering diet before starting treatment with Zocor and continue this diet while using Zocor.

All doses should be adjusted to your individual needs.

ADULTS

The usual starting dose is 20 to 40 milligrams once a day in the evening. If your cholesterol level or heart attack risk is especially high, the doctor may start with a dose of 40 milligrams. The dosage can be adjusted every 4 weeks. Some people with severe, hereditary high cholesterol may be prescribed as much as 80 milligrams a day, taken in doses of 20, 20, and 40 milligrams, along with other treatments.

Those who have severe kidney disease should use Zocor with caution. The recommended starting dose is 5 milligrams per day.

When combined with cyclosporine, niacin, Atromid-S, Lopid, or Tricor, the dosage of Zocor should not exceed 10 milligrams a day. When combined with Calan or Cordarone, the dosage of Zocor should not exceed 20 milligrams a day.

CHILDREN 10 TO 17 YEARS OLD

The recommended starting dose is 10 milligrams once a day in the evening. The dosage may be increased every 4 weeks, as determined by the doctor, up to a maximum of 40 milligrams a day. Girls must have been menstruating for at least 1 year before starting therapy with Zocor.

The safety and effectiveness of Zocor in children under 10 years old or in doses greater than 40 milligrams a day have not been studied.

Overdosage

Although no specific information about Zocor overdose is available, any medication taken in excess can have serious consequences. If you suspect an overdose of Zocor, seek medical attention immediately.

 Zocor

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Isoxsuprine is in a class of drugs called vasodilators. Isoxsuprine relaxes veins and arteries, which makes them wider and allows blood to pass through them more easily.

These actions may help treat the symptoms of conditions such as cerebral vascular insufficiency (poor blood flow to the brain), arteriosclerosis (hardening of the arteries), Raynaud’s phenomenon, and other conditions involving poor blood flow in the veins and arteries.

Isoxsuprine may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about Vasodilan (isoxsuprine)?

Use caution when driving, operating machinery, or performing other hazardous activities. Isoxuprine may cause dizziness. If you experience dizziness, avoid these activities. Also, rise slowly from a sitting or lying position to avoid falling.

Notify your doctor if you experience a rash or bothersome irregular heartbeats.

Isoxsuprine has been withdrawn from the U.S. market.

What should I discuss with my healthcare provider before taking Vasodilan (isoxsuprine)?

Isoxsuprine should not be used immediately postpartum (after delivering a baby), or if you have a bleeding disorder. Talk to your doctor about any other medical conditions that you have.

Isoxsuprine is in the FDA pregnancy category C. This means that it is not known whether isoxsuprine will be harmful to an unborn baby. Do not take this medication without first talking to your doctor if you are pregnant or could become pregnant during treatment. It is not known whether isoxsuprine passes into breast milk. Do not take this medication without first talking to your doctor if you are breast-feeding a baby.

How should I take Vasodilan (isoxsuprine)?

Take isoxsuprine exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

Take each dose with a full glass of water. Isoxsuprine is usually taken three or four times a day. Follow your doctor’s instructions.It is important to take isoxsuprine regularly to get the most benefit.

Your doctor may want you to have blood tests or other medical evaluations during treatment with isoxsuprine to monitor progress and side effects.

Store isoxsuprine at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take only the next regularly scheduled dose. Do not take a double dose of this medication.

What happens if I overdose?

Seek emergency medical attention if an overdose is suspected.

Symptoms of an isoxsuprine overdose include weakness, lightheadedness, fainting, nausea, and vomiting.

What should I avoid while taking Vasodilan (isoxsuprine)?

Use caution when driving, operating machinery, or performing other hazardous activities. Isoxsuprine may cause dizziness. If you experience dizziness, avoid these activities. Also, rise slowly from a sitting or lying position to avoid falling.

Vasodilan (isoxsuprine) side effects

Stop taking isoxsuprine and seek emergency medical attention if you experience an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives).Stop taking isoxsuprine and contact your doctor if you develop a rash.

Other, less serious side effects may be more likely to occur. Continue to take isoxsuprine and talk to your doctor if you experience

• chest pain or an irregular heartbeat (call your doctor if this becomes bothersome);
• nausea or vomiting; or
• dizziness or weakness.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect Vasodilan (isoxsuprine)?

Drugs used to treat high blood pressure and other heart conditions may increase the effects of isoxsuprine. Special monitoring may be necessary.

Drugs other than those listed here may also interact with isoxsuprine or affect your condition. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including vitamins, minerals, and herbal products.

 Vasodilan

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Penisole is a 100% Natural and Safe Product that can safely and permanently enlarge your penis size up to 1-3 Inches in length and up to 25% in girth.

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How Taken

2 caps after meal or as directed by the physician.

Drug Class and Mechanism

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Missed Dose

If you miss a dose of Penisole, skip the missed dose. Go back to your regular dosing schedule. Do not take 2 doses at once.

Storage

Store Penisole at 77 degrees F (25 degrees C). Brief storage between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Penisole out of the reach of children and away from pets.

Warnings Precautions

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Possible Side Effects

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More Information

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Penisole

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