Nolvadex, an anticancer drug, is given to treat breast cancer. It also has proved effective when cancer has spread to other parts of the body. Nolvadex is most effective in stopping the kind of breast cancer that thrives on estrogen.

Nolvadex is also prescribed to reduce the risk of invasive breast cancer following surgery and radiation therapy for ductal carcinoma in situ. The drug can also be used to reduce the odds of breast cancer in women at high risk of developing the disease. It does not completely eliminate your chances, but in a five-year study of over 1,500 high-risk women, it slashed the number of cases by 44 percent.

Most important fact about Nolvadex

Although Nolvadex reduces the risk of breast cancer, it increases the possibility of developing endometrial (uterine) cancer. Women taking Nolvadex should have routine gynecological examinations and report any abnormal vaginal bleeding, changes in menstrual periods, change in vaginal discharge, or pelvic pain or pressure to the doctor immediately. Even after Nolvadex therapy has stopped, any abnormal vaginal bleeding should be reported at once.

How should you take Nolvadex?

Take Nolvadex exactly as prescribed. Do not stop taking this medication without first consulting your doctor. It may be necessary to continue taking the drug for several years.

• If you miss a dose…
  Do not try to make it up. Go back to your regular schedule with the next dose.

• Storage instructions…
  Nolvadex may be stored at room temperature.

What side effects may occur?

Side effects from Nolvadex are usually mild and rarely require the drug to be stopped. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Nolvadex.

• Side effects may include:
  Hot flashes, nausea, vomiting

Special information if you are pregnant or breastfeeding

It is important to avoid pregnancy while taking Nolvadex, because the drug could harm the unborn child. Since Nolvadex is an anti-estrogen drug, you will need to use a non-hormonal form of contraception, such as a condom and/or diaphragm, and not birth control pills. If you accidentally become pregnant while taking Nolvadex, or within 2 months after you have stopped taking it, discuss this with your doctor immediately.

Because Nolvadex might cause serious harm to a nursing infant, you should not breastfeed your baby while taking this drug. If this medication is essential to your health, your doctor may advise you to discontinue breastfeeding until your treatment is finished.

Recommended dosage for Nolvadex

 ADULTS

Breast Cancer Treatment

The daily dosage ranges from 20 to 40 milligrams. If you are taking more than 20 milligrams a day, your doctor will have you divide the total into 2 smaller doses taken in the morning and evening. Nolvadex comes in 10- and 20-milligram tablets.

Ductal Carcinoma in Situ

The recommended dose is 20 milligrams once daily for 5 years.

Breast Cancer Prevention

The recommended dose is 20 milligrams once a day for up to 5 years.

CHILDREN

Safety and efficacy in children have not been established.

Overdosage

Any medication taken in excess can have serious consequences. If you suspect an overdose of Nolvadex, seek medical attention immediately.

• Symptoms of Nolvadex overdose may include:
  Dizziness, overactive reflexes, tremor, unsteady gait

Nolvadex

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