Celebrex is prescribed for acute pain, menstrual cramps, and the pain and inflammation of osteoarthritis and rheumatoid arthritis. It is a member of a new class of nonsteroidal anti-inflammatory drugs (NSAIDs) called COX-2 inhibitors. Like older NSAIDs such as Motrin and Naprosyn, Celebrex is believed to fight pain and inflammation by inhibiting the effect of a natural enzyme called COX-2. Unlike the older medications, however, it does not interfere with a similar substance, called COX-1, which exerts a protective effect on the lining of the stomach. Therefore, Celebrex may be less likely to cause the bleeding and ulcers that sometimes accompany sustained use of the older NSAIDs.

Celebrex has also been found to reduce the number of colorectal polyps (growths in the wall of the lower intestine and rectum) in people who suffer from the condition called familial adenomatous polyposis (FAP), an inherited tendency to develop large numbers of colorectal polyps that eventually become cancerous.

Most important fact about Celebrex

Like other NSAID medication, Celebrex could increase the chance of having a heart attack or stroke, possibly resulting in death. The risk is greater if you have heart disease or use NSAIDs for a long time. It’s important to discuss the risks and benefits of using Celebrex with your doctor and to use the lowest effective dose for the shortest amount of time possible.

Although Celebrex is easy on the stomach, it still poses some degree of risk—especially if you’ve had a stomach ulcer or gastrointestinal bleeding in the past. All NSAIDs, including Celebrex, can cause serious—and even life-threatening—ulcers and bleeding in the stomach and intestines. These side effects can happen without symptoms and may occur at any time during treatment. If you’ve ever had ulcers or stomach bleeding, make sure the doctor is aware of it. And be sure to alert the doctor if you develop any digestive problems or notice a change in your bowel movement (such as blood in the stool or black, sticky stools).

How should you take Celebrex?

Take Celebrex exactly as prescribed. You can take it with or without food.

–If you miss a dose…

Take it as soon as you remember. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Do not take 2 doses at the same time.

What side effects may occur?

Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Celebrex.

• More common side effects may include:
  Abdominal pain, diarrhea, headache, indigestion, nausea, respiratory infection, sinus inflammation

Special information if you are pregnant or breastfeeding

Celebrex can harm a developing baby if taken during the third trimester, and its safety earlier in pregnancy has not been confirmed. Take it during pregnancy only if you feel the risk is justified.

It’s possible that Celebrex makes its way into breast milk (limited data from one subject indicated that the drug was excreted in human milk), and it could cause serious reactions in a nursing infant. If this drug is essential to your health, your doctor may advise you to discontinue breastfeeding.

Recommended dosage

The following dosages are typically cut in half for people with moderate liver problems.

ADULTS

Osteoarthritis

The recommended daily dose is 200 milligrams, taken as a single dose or in 100-milligram doses twice a day.

Rheumatoid Arthritis

The recommended dose is 100 to 200 milligrams twice a day.

Acute Pain and Menstrual Cramps

The recommended starting dose is 400 milligrams, followed by an additional 200 milligrams if needed on the first day. On subsequent days, the recommended dosage is 200 milligrams twice a day.

Familial Adenomatous Polyposis

The recommended dose is 400 milligrams twice a day with food.

Overdosage

Any medication taken in excess can have serious consequences. If you suspect an overdose, seek medical attention immediately.

• Symptoms of Celebrex overdose may include:
  Breathing difficulties, coma, drowsiness, gastrointestinal bleeding, high blood pressure, kidney failure, nausea, sluggishness, stomach pain, vomiting

Celebrex

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Rumalaya tablet is useful in the following conditions: rheumatic arthritis; rheumatoid arthritis; cervical and lumbar spondylosis; osteoarthritis; arthralgia; gout; frozen shoulder; traumatic inflammatory conditions like fibrositis, bursitis, synovitis, capsulitis, tenosynovitis, myositis and sciatica.

How Taken

1 tablet twice daily, preferably with meals.

Drug Class and Mechanism

Rumalaya possesses analgesic and anti-arthritic properties. By regulating the mediators of inflammation, Rumalaya exerts a significant anti-inflammatory activity.

Missed Dose

If you miss a dose of this medicine and you are using it regularly, take it as soon as possible. Do not take 2 doses at once.

Storage

Store at the room temperature away from moisture and sunlight. Keep out of the reach of children.

Warnings Precautions

No absolute contraindications. Consult your healthcare professional if pregnant or nursing.

Possible Side Effects

Rumalaya is not known to have any side effects if taken as per the prescribed dosage.

More Information

Rumalaya helps support connective tissue and alleviates the discomfort, caused by impaired movement. Joint discomfort is a widespread occurrence that can result from such factors as climate, lifestyle, work habits, or repetitive movement. Taken daily as a dietary supplement, Rumalaya has demonstrated positive results in relieving discomfort, caused by morning stiffness (results are gradual but long lasting).

Rumalaya

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Mobic is in a group of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs). Mobic works by reducing hormones that cause inflammation and pain in the body.

Mobic is used to treat pain or inflammation caused by arthritis.

Mobic may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about Mobic?

This medicine can increase your risk of life-threatening heart or circulation problems, including heart attack or stroke. Do not use this medicine just before or after having heart bypass surgery (also called coronary artery bypass graft, or CABG).

Seek emergency medical help if you have symptoms of heart or circulation problems, such as chest pain, weakness, shortness of breath, slurred speech, or problems with vision or balance.

This medicine can also increase your risk of serious effects on the stomach or intestines, including bleeding or perforation (forming of a hole). These conditions can be fatal and gastrointestinal effects can occur without warning at any time while you are taking Mobic. Older adults may have an even greater risk of these serious gastrointestinal side effects.

Call your doctor at once if you have symptoms of bleeding in your stomach or intestines. This includes black, bloody, or tarry stools, or coughing up blood or vomit that looks like coffee grounds.

What should I discuss with my healthcare provider before taking Mobic?

Taking an NSAID can increase your risk of life-threatening heart or circulation problems, including heart attack or stroke. This risk will increase the longer you use an NSAID. Do not use this medicine just before or after having heart bypass surgery (also called coronary artery bypass graft, or CABG).

NSAIDs can also increase your risk of serious effects on the stomach or intestines, including bleeding or perforation (forming of a hole). These conditions can be fatal and gastrointestinal effects can occur without warning at any time while you are taking an NSAID. Older adults may have an even greater risk of these serious gastrointestinal side effects.

Do not use Mobic if you are allergic to meloxicam, or to aspirin or other NSAIDs.

Before taking Mobic, tell your doctor if you are allergic to any drugs, or if you have:

• a history of heart attack, stroke, or blood clot;
• heart disease, congestive heart failure, high blood pressure;
• a history of stomach ulcers or bleeding, bowel problems, diverticulosis;
• liver or kidney disease;
• asthma;
• polyps in your nose; or
• if you smoke.

If you have any of these conditions, you may need a dose adjustment or special tests to safely take Mobic.

FDA pregnancy category C. Mobic may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Taking Mobic during the last 3 months of pregnancy may result in birth defects. Do not take Mobic during pregnancy unless your doctor has told you to. Mobic can pass into breast milk and may harm a nursing baby. Do not use Mobic without telling your doctor if you are breast-feeding a baby. Do not give this medicine to a child younger than 2 years old without the advice of a doctor.

How should I take Mobic?

Take Mobic exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label. The maximum amount of Mobic for adults is 15 milligrams (mg) per day. Know the amount of Mobic in the specific product you are taking.

If you take Mobic for a long period of time, your doctor may want to check you on a regular basis to make sure Mobic is not causing harmful effects. Do not miss any scheduled appointments.

This medication can cause you to have unusual results with certain medical tests. Tell any doctor who treats you that you are using Mobic.

Store Mobic at room temperature, away from moisture, heat, and light.

What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at your next regularly scheduled time. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine. Overdose symptoms may include nausea, vomiting, dizziness, drowsiness, black or bloody stools, coughing up blood, fever, urinating less than usual or not at all, shallow breathing, fainting, seizure (convulsions), or coma.

Mobic side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop taking Mobic and seek medical attention or call your doctor at once if you have any of these serious side effects:

• chest pain, weakness, shortness of breath, slurred speech, problems with vision or balance;
• black, bloody, or tarry stools, coughing up blood or vomit that looks like coffee grounds;
• urinating less than usual or not at all;
• nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
• fever, sore throat, and headache with a severe blistering, peeling, and red skin rash; or
• bruising, severe tingling, numbness, pain, muscle weakness.

Less serious side effects may include:

• upset stomach, mild heartburn or stomach pain, diarrhea, constipation; bloating, gas;
• dizziness, headache, nervousness;
• skin itching or rash;
• dry mouth;
• increased sweating, runny nose;
• blurred vision; or
• ringing in your ears.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect.

What other drugs will affect Mobic?

Before taking Mobic, tell your doctor if you are taking any of the following drugs:

• cyclosporine (Gengraf, Neoral, Sandimmune);
• lithium (Eskalith, Lithobid);
• diuretics (water pills) such as furosemide (Lasix);
• glyburide (DiaBeta, Micronase);
• methotrexate (Rheumatrex, Trexall);
• a blood thinner such as warfarin (Coumadin);
• steroids (prednisone and others);
• an ACE inhibitor such as benazepril (Lotensin), captopril (Capoten), fosinopril (Monopril), enalapril (Vasotec), lisinopril (Prinivil, Zestril), moexipril (Univasc), perindopril (Aceon), quinapril (Accupril), ramipril (Altace), or trandolapril (Mavik); or
• aspirin or other NSAIDs (non-steroidal anti-inflammatory drugs) such as diclofenac (Voltaren), etodolac (Lodine), ibuprofen (Advil, Motrin), indomethacin (Indocin), ketoprofen (Orudis), naproxen (Aleve, Naprosyn), and others.

This list is not complete and there may be other drugs that can interact with Mobic. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Mobic

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The following items has been added to the shops:

Foradil
FML Forte
Floxin
Estrace
Entocort
Digoxin
Torsemide
Tetracycline
Antivert
Meclizine
Imodium
Doxazosin

The following items came back:

Flovent
Lanoxin

Drugstore

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