Decadron, a corticosteroid drug, is used to reduce inflammation and relieve symptoms in a variety of disorders, including rheumatoid arthritis and severe cases of asthma. It may be given to people to treat primary or secondary adrenal cortex insufficiency (lack of sufficient adrenal hormone). It is also given to help treat the following disorders:

Severe allergic conditions such as drug-induced allergies
Blood disorders such as various anemias
Certain cancers (along with other drugs)
Skin diseases such as severe psoriasis
Collagen (connective tissue) diseases such as systemic lupus erythematosus
Digestive tract disease such as ulcerative colitis
High serum levels of calcium associated with cancer
Fluid retention due to nephrotic syndrome (a condition in which damage to the kidneys causes the body to lose protein in the urine)
Eye diseases such as allergic conjunctivitis
Lung diseases such as tuberculosis (along with other drugs)

Most important fact about Decadron Tablets

Decadron lowers your resistance to infections and can make them harder to treat. Decadron may also mask some of the signs of an infection, making it difficult for your doctor to diagnose the actual problem.

How should you take Decadron Tablets?

Decadron should be taken exactly as prescribed by your doctor.

If you are taking large doses, your doctor may advise you to take Decadron with meals and to take antacids between meals, to prevent a peptic ulcer from developing.

Check with your doctor before stopping Decadron abruptly. If you have been taking the drug for a long time, you may need to reduce your dose gradually over a period of days or weeks.

The lowest possible dose should always be used, and as symptoms subside, dosage should be reduced gradually.

–If you miss a dose…

Take the forgotten dose as soon as you remember. If it is almost time for the next dose, skip the one you missed and go back to your regular schedule. Never try to “catch up” by doubling the dose.

What side effects may occur?

Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Decadron.

• More common side effects may include:
  Abdominal distention, allergic reactions, blood clots, bone fractures and degeneration, bruises, cataracts, congestive heart failure, convulsions, “cushingoid” symptoms (moon face, weight gain, high blood pressure, emotional disturbances, growth of facial hair in women), excessive hairiness, fluid and salt retention, general feeling of illness, glaucoma, headache, hiccups, high blood pressure, high blood sugar, hives, increased appetite, increased eye pressure, increased pressure in head, increased sweating, increases in amounts of insulin or hypoglycemic medications needed in diabetes, inflammation of the esophagus, inflammation of the pancreas, irregular menstruation, loss of muscle mass, low potassium levels in blood (leading to symptoms such as dry mouth, excessive thirst, weak or irregular heartbeat, and muscle pain or cramps), muscle weakness, nausea, osteoporosis, peptic ulcer, perforated small and large bowel, poor healing of wounds, protruding eyeballs, suppression of growth in children, thin skin, tiny red or purplish spots on the skin, torn tendons, vertigo, weight gain

Special information if you are pregnant or breastfeeding

The effects of Decadron during pregnancy have not been adequately studied. If you are pregnant or plan to become pregnant, inform your doctor immediately. Infants born to mothers who have taken substantial doses of corticosteroids during pregnancy should be carefully watched for adrenal problems. Corticosteroids appear in breast milk and can suppress growth in infants. If Decadron is essential to your health, your doctor may advise you to stop breastfeeding until your treatment with Decadron is finished.

Recommended dosage

ADULTS

Your doctor will tailor your individual dose to the condition being treated. Initial doses range from 0.75 milligram to 9 milligrams a day.

After the drug produces a satisfactory response, your doctor will gradually lower the dose to the minimum effective level.

Overdosage

Reports of overdose with this medication are rare. However, if you suspect an overdose, seek medical treatment immediately.

Decadron

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Flexisyn is designed to alleviate the pain and inflammation associated with Arthritis, thereby effecting over time, a possible increase in a sufferers mobility and flexibility.

How Taken

Consult your healthcare provider to establish your personal dosage.

Drug Class and Mechanism

Flexisyn contains safe and natural Cox-2 inhibitors, such as Feverfew and Turmeric, and antiinflammatory herbs, such as Cat’s Claw and Licorice root. Formulated to be safe and effective, the ingredients in Flexisyn can provide relief from the joint pain and inflammation associated with rheumatoid arthritis and osteoarthritis without the negative side effects of prescription drugs.

Flexisyn treats the Stevens-Johnson syndrome, a skin disorder, caused by BEXTRA (valdecoxib), and potential heart problems associated with CELEBREX (celecoxib).

Missed Dose

If you miss a dose of Flexisyn, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Storage

Store Flexisyn at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Keep Flexisyn out of the reach of children and away from pets.

Warnings Precautions

Seek the advice of a health care professional if you have any medical condition.

Possible Side Effects

Because Flexisyn is an all-natural nutritional supplement containing only the finest botanicals, there are no harmful side effects when taken as directed.

More Information

Flexisyn is not a pharmaceutical drug and contains none of the synthetic chemicals found in prescription medications. It is a safe alternative to prescription drugs, which can sometimes have serious side effects.

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Probenecid reduces the amount of uric acid in your body by causing more uric acid to be passed out in your urine.

Probenecid is used to treat gout and gouty arthritis. Probenecid is also used to increase the effectiveness of some antibiotics.

Probenecid may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about Benemid (probenecid)?

To reduce the risk that kidney stones will form, drink at least 8 to 10 full glasses (8 ounces) of fluid every day, unless your doctor tells you not to. Take probenecid with food or an antacid to lessen stomach upset. Do not take aspirin, salsalate (Disalcid), magnesium salicylate (Magan, Doan’s), choline and magnesium salicylate (Trilisate), or other aspirin-like products unless your doctor approves. These products decrease the effects of probenecid. Taking one aspirin a day to reduce the risk of a heart attack is usually acceptable, if prescribed by your doctor.

What should I discuss with my healthcare provider before taking Benemid (probenecid)?

Before taking this medication, tell your doctor if you

• have ever had an allergic reaction to probenecid,
• have kidney disease or poorly functioning kidneys,
• have kidney stones,
• have an ulcer in your stomach,
• have blood problems, or
• are on high-dose aspirin or salicylate therapy.

You may not be able to take probenecid, or you may require a lower dose or special monitoring during treatment if you have any of the conditions listed above.

Probenecid is in the FDA pregnancy category B. This means that it is not expected to harm an unborn baby. Do not take probenecid without first talking to your doctor if you are pregnant. It is not known whether probenecid will harm a nursing baby. Do not take probenecid without first talking to your doctor if you are breast-feeding a baby. Probenecid is not approved for use by children younger than 2 years of age.

How should I take Benemid (probenecid)?

Take probenecid exactly as directed by your doctor. If you do not understand the directions on your prescription bottle, ask your pharmacist, nurse, or doctor to explain them to you.

Take each dose of probenecid with a full glass of water. Also, to reduce the risk of kidney stone formation, drink at least 8 to 10 full glasses (8 ounces) of fluid every day, unless your doctor tells you not to. Take probenecid with food or with an antacid to lessen stomach upset. If nausea, vomiting, or loss of appetite is severe or persistent, consult your doctor. Store probenecid at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the dose you missed and take only your next regularly scheduled dose. Do not take a double dose of this medication.

What happens if I overdose?

Seek emergency medical attention.

Symptoms of a probenecid overdose include nausea, vomiting, seizures, and coma. An overdose of probenecid can result in death.

Benemid (probenecid) side effects

If you experience any of the following serious side effects, stop taking probenecid and seek emergency medical attention:

• an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);
• blood in your urine or pain when you urinate; or
• a rash or hives.

Other, less serious side effects may be more likely to occur. Continue to take probenecid and talk to your doctor if you experience

• mild nausea, vomiting, or loss of appetite;
• headache or dizziness;
• sore gums;
• flushing; or
• an acute gouty arthritis attack.

Side effects other than those listed here may also occur. Talk to your doctor about any reaction that seems unusual or that is especially bothersome.

What other drugs will affect Benemid (probenecid)?

Do not take aspirin, salsalate (Disalcid), magnesium salicylate (Magan, Doan’s), choline and magnesium salicylate (Trilisate), or other aspirin-like products unless your doctor approves. These products decrease the effects of probenecid. Taking, one aspirin a day to reduce the risk of a heart attack is usually acceptable, if prescribed by your doctor.

Probenecid may increase the effects of many other drugs by preventing their removal through the kidneys. This could lead to dangerous side effects. Before taking probenecid, tell your doctor if you are taking any of the following medicines:

• acyclovir (Zovirax);
• allopurinol (Zyloprim);
• penicillamine (Cuprimine);
• clofibrate (Atromid-S);
• rifampin (Rifadin, Rimactane);
• methotrexate (Rheumatrex);
• zidovudine (Retrovir);
• acetaminophen (Tylenol, many others);
• theophylline (Slo-Bid, Theo-Dur, Elixophyllin, Slo-Phyllin, Theolair, Theochron, others);
• dapsone;
• a penicillin or cephalosporin antibiotic such as amoxicillin (Amoxil, Trimox, Augmentin, others), ampicillin (Principen, others), cephalexin (Keflex), cefuroxime (Ceftin), cefpodoxime (Vantin), cefixime (Suprax), and others;
• a nonsteroidal anti-inflammatory drug (NSAID) such as ibuprofen (Motrin, Advil, Nuprin, others), ketoprofen (Orudis, Oruvail, Orudis KT), diclofenac (Cataflam, Voltaren), etodolac (Lodine), fenoprofen (Nalfon), flurbiprofen (Ansaid), indomethacin (Indocin), ketorolac (Toradol), nabumetone (Relafen), oxaprozin (Daypro), piroxicam (Feldene), sulindac (Clinoril), tolmetin (Tolectin), and naproxen (Aleve, Anaprox, Naprosyn);
• a sulfa-based medication such as sulfamethoxazole (Bactrim, Septra, Gantanol), sulfasalazine (Azulfidine), sulfinpyrazone (Anturane), sulfisoxazole (Gantrisin), and others;
• an oral diabetes medicine such as glipizide (Glucotrol), glyburide (Micronase, Diabeta, Glynase), tolbutamide (Orinase), or tolazamide (Tolinase);
• a barbiturate such as phenobarbital (Luminal, Solfoton), amobarbital (Amytal), secobarbital (Seconal), and others; or
• a benzodiazepine (used to treat anxiety and panic disorders and to induce sleep) such as alprazolam (Xanax), diazepam (Valium), lorazepam (Ativan), temazepam (Restoril), chlordiazepoxide (Librium), clonazepam (Klonopin), clorazepate (Tranxene), oxazepam (Serax), estazolam (ProSom), flurazepam (Dalmane), quazepam (Doral), or triazolam (Halcion).

You may require a dosage adjustment or special monitoring during your treatment if you are taking any of the medicines listed above.

Drugs other than those listed here may also interact with probenecid. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.

Benemid

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