Triamcinolone is in a class of drugs called steroids. Triamcinolone prevents the release of substances in the body that cause inflammation.

Triamcinolone is used to treat many different conditions such as allergic disorders, skin conditions, ulcerative colitis, arthritis, lupus, psoriasis, or breathing disorders.

Triamcinolone may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about Aristocort (Triamcinolone)?

You should not use this medication if you are allergic to triamcinolone, or if you have a fungal infection anywhere in your body.

Before taking triamcinolone, tell your doctor about all of your medical conditions, and about all other medicines you are using. There are many other disease that can be affected by steroid use, and many other medicines that can interact with steroids.

Your steroid medication needs may change if you have any unusual stress such as a serious illness, fever or infection, or if you have surgery or a medical emergency. Tell your doctor about any such situation that affects you during treatment.

Steroid medication can weaken your immune system, making it easier for you to get an infection or worsening an infection you already have or have recently had. Tell your doctor about any illness or infection you have had within the past several weeks.

Avoid being near people who are sick or have infections. Call your doctor for preventive treatment if you are exposed to chicken pox or measles. These conditions can be serious or even fatal in people who are using steroid medication.

Do not receive a “live” vaccine while you are taking triamcinolone. Vaccines may not work as well while you are taking a steroid.

Do not stop using triamcinolone suddenly, or you could have unpleasant withdrawal symptoms. Talk to your doctor about how to avoid withdrawal symptoms when stopping the medication. Carry an ID card or wear a medical alert bracelet stating that you are taking a steroid, in case of emergency.

What should I discuss with my healthcare provider before taking Aristocort (Triamcinolone)?

You should not use this medication if you are allergic to triamcinolone, or if you have a fungal infection anywhere in your body.

Steroid medication can weaken your immune system, making it easier for you to get an infection. Steroids can also worsen an infection you already have, or reactivate an infection you recently had. Before taking this medication, tell your doctor about any illness or infection you have had within the past several weeks.

Other medical conditions you should tell your doctor about before taking triamcinolone include:

• liver disease (such as cirrhosis);
• kidney disease;
• a thyroid disorder;
• diabetes;
• a history of malaria;
• tuberculosis;
• osteoporosis;
• a muscle disorder such as myasthenia gravis;
• glaucoma or cataracts;
• herpes infection of the eyes;
• stomach ulcers, ulcerative colitis, or diverticulitis;
• depression or mental illness;
• congestive heart failure; or
• high blood pressure

If you have any of these conditions, you may need a dose adjustment or special tests to safely take triamcinolone.

FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Triamcinolone can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Steroids can affect growth in children. Talk with your doctor if you think your child is not growing at a normal rate while using this medication.

How should I take Aristocort (Triamcinolone)?

Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.

Your doctor may occasionally change your dose to make sure you get the best results from this medication.

Your steroid medication needs may change if you have unusual stress such as a serious illness, fever or infection, or if you have surgery or a medical emergency. Tell your doctor about any such situation that affects you.

This medication can cause you to have unusual results with certain medical tests. Tell any doctor who treats you that you are using triamcinolone.

Do not stop using triamcinolone suddenly, or you could have unpleasant withdrawal symptoms. Talk to your doctor about how to avoid withdrawal symptoms when stopping the medication. Carry an ID card or wear a medical alert bracelet stating that you are taking a steroid, in case of emergency. Any doctor, dentist, or emergency medical care provider who treats you should know that you are taking steroid medication. Store triamcinolone at room temperature away from moisture and heat.

What happens if I miss a dose?

If you miss a dose or forget to take your medicine, contact your doctor or pharmacist for instructions.

What happens if I overdose?

Seek emergency medical attention if you think you have received too much of this medicine.

A single large dose of triamcinolone is not expected to produce life-threatening symptoms. However, high doses taken over a long period of time may cause weight gain, roundness of the face, increased facial hair growth, bruising, swelling, and muscle pain or weakness.

Aristocort (Triamcinolone) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have any of these serious side effects:

• problems with your vision;
• swelling, rapid weight gain, feeling short of breath;
• severe depression, unusual thoughts or behavior, seizure (convulsions);
• bloody or tarry stools, coughing up blood;
• pancreatitis (severe pain in your upper stomach spreading to your back, nausea and vomiting, fast heart rate);
• low potassium (confusion, uneven heart rate, extreme thirst, increased urination, leg discomfort, muscle weakness or limp feeling); or
• dangerously high blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, confusion, chest pain, shortness of breath, uneven heartbeats, seizure).

Less serious side effects may include:

• sleep problems (insomnia), mood changes;
• acne, dry skin, thinning skin, bruising or discoloration;
• slow wound healing;
• increased sweating;
• headache, dizziness, spinning sensation;
• nausea, stomach pain, bloating;
• muscle weakness;
• changes in the shape or location of body fat (especially in your arms, legs, face, neck, breasts, and waist);

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect.

What other drugs will affect Aristocort (Triamcinolone)?

There are many other medicines that can interact with steroids. Below is only a partial list of these medicines:

• aspirin (taken on a daily basis or at high doses);
• a diuretic (water pill);
• a blood thinner such as warfarin (Coumadin);
• cyclosporine (Gengraf, Neoral, Sandimmune);
• insulin or diabetes medications you take by mouth;
• antibiotics such as ketoconazole (Nizoral), rifampin (Rifadin, Rifater, Rifamate, Rimactane), or troleandomycin (Tao); or
• seizure medications such as phenytoin (Dilantin) or phenobarbital (Luminal, Solfoton).

This list is not complete and there may be other drugs that can interact with triamcinolone. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

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Fexofenadine is an antihistamine that reduces the natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Fexofenadine is used to treat the symptoms of seasonal allergies (hay fever) in adults and children.

Fexofenadine is also used to treat skin itching and hives caused by a condition called chronic idiopathic urticaria in adults and children.

Fexofenadine may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about Allegra (Fexofenadine)?

Before using fexofenadine, tell your doctor if you are allergic to any drugs, or if you have kidney disease.

Fruit juices and certain antacids can make it harder for your body to absorb fexofenadine. Take the disintegrating tablet on an empty stomach, at least 1 hour before or 2 hours after a meal.

There may be other drugs that can affect fexofenadine. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Stop using this medication and get emergency medical help if you think you have used too much medicine, or if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Less serious side effects are more likely, and you may have none at all. Tell your doctor about any unusual or bothersome side effect.

Tell your doctor if your symptoms do not improve, or if they get worse after you start taking fexofenadine. Never take more of the medication than your doctor has prescribed.

What should I discuss with my healthcare provider before taking Allegra (Fexofenadine)?

Before using fexofenadine, tell your doctor if you are allergic to any drugs, or if you have kidney disease.

FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether fexofenadine passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Fexofenadine tablets and capsules may be used to treat seasonal allergy symptoms in children who are at least 6 years old. Fexofenadine oral suspension (liquid) may be used in children ages 2 through 11. When treating chronic idiopathic urticaria, the liquid may be used in children as young as 2 months old.

How should I take Allegra (Fexofenadine)?

Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.

Take the regular tablet with a full glass of water. Do not use any other type of liquid. Shake the oral suspension (liquid) well just before you measure a dose. To be sure you get the correct dose, measure the liquid with a marked measuring spoon or medicine cup, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

To take fexofenadine orally disintegrating tablets (Allegra ODT):

• Keep the tablet in its blister pack until you are ready to take the medicine. Open the package and peel back the foil from the tablet blister. Do not push a tablet through the foil or you may damage the tablet.
• Using dry hands, remove the tablet and place it in your mouth. It will begin to dissolve right away.
• Do not swallow the tablet whole. Allow it to dissolve in your mouth without chewing.
• Swallow several times as the tablet dissolves. If desired, you may drink liquid to help swallow the dissolved tablet.

Take the disintegrating tablet on an empty stomach, at least 1 hour before or 2 hours after a meal.

Tell your doctor if your symptoms do not improve, or if they get worse after you start taking fexofenadine. Never take more of the medication than your doctor has prescribed.

Store fexofenadine at room temperature away from moisture and heat. Keep the medicine bottle tightly closed.

What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at your next regularly scheduled time. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include dry mouth, dizziness, or drowsiness.

Allegra (Fexofenadine) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop taking fexofenadine and call your doctor if you have fever, chills, body aches, cough, or other flu symptoms.

Less serious side effects may include:

• nausea, diarrhea, upset stomach;
• menstrual cramps;
• drowsiness, tired feeling;
• headache; or
• muscle or back pain.

This list is not complete and other side effects may occur. Tell your doctor about any unusual or bothersome side effect.

What other drugs will affect Allegra (Fexofenadine)?

Before taking fexofenadine, tell your doctor if you are also taking ketoconazole (Nizoral), or erythromycin (E-Mycin, E.E.S., Ery-Tab, Erythrocin).

There may be other drugs that can interact with fexofenadine. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.

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Loratadine is an antihistamine that reduces the natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Loratadine is used to treat the symptoms of allergies, such as sneezing, watery eyes, and runny nose. It is also used to treat skin hives and itching in people with chronic skin reactions.

Loratadine may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about Alavert (loratadine)?

You should not take this medication if you are allergic to loratadine or to desloratadine (Clarinex).

Before taking loratadine, tell your doctor if you are allergic to any drugs, or if you have liver or kidney disease.

Do not give this medication to a child younger than 6 years old without the advice of a doctor.

Loratadine disintegrating tablets (Claritin Reditab) may contain phenylalanine. Talk to your doctor before using this form of loratadine if you have phenylketonuria (PKU).

What should I discuss with my healthcare provider before taking Alavert (loratadine)?

You should not take this medication if you are allergic to loratadine or to desloratadine (Clarinex).

Before taking loratadine, tell your doctor if you are allergic to any drugs, or if you have:

• kidney disease; or
• liver disease.

If you have any of these conditions, you may need a dose adjustment or special tests to safely take loratadine.

FDA pregnancy category B: This medication is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Loratadine can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Loratadine disintegrating tablets (Claritin Reditab, Alavert) may contain phenylalanine. Talk to your doctor before using this form of loratadine if you have phenylketonuria (PKU).

Do not give this medication to a child younger than 6 years old without the advice of a doctor.

How should I take Alavert (loratadine)?

Take this medication as directed on the label, or as your doctor has prescribed. Do not take the medication in larger amounts or for longer than recommended.

Loratadine is usually taken once per day. Follow your doctor’s instructions.

Do not crush, chew, or break the regular loratadine tablet. Swallow the pill whole.

Measure liquid form of loratadine with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

To take loratadine orally disintegrating tablet (Claritin RediTab, Alavert):

• Keep the tablet in its blister pack until you are ready to take the medicine. Open the package and peel back the foil from the tablet blister. Do not push a tablet through the foil or you may damage the tablet.
• Using dry hands, remove the tablet and place it on your tongue. It will begin to dissolve right away.
• Do not swallow the tablet whole. Allow it to dissolve in your mouth without chewing.
• Swallow several times as the tablet dissolves. If desired, you may drink water to help swallow the dissolved tablet.

Call your doctor if your symptoms do not improve.

Store loratadine at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to take the medicine and skip the missed dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include headache, drowsiness, and fast or pounding heartbeat.

Alavert (loratadine) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have any of these serious side effects:

• fast or uneven heart rate;
• feeling like you might pass out;
• jaundice (yellowing of your skin or eyes); or
• seizures (convulsions).

Less serious side effects may include:

• headache;
• nervousness;
• feeling tired or drowsy;
• stomach pain, diarrhea;
• dry mouth, sore throat hoarseness;
• eye redness, blurred vision;
• nosebleed; or
• skin rash.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect.

What other drugs will affect Alavert (loratadine)?

There may be other drugs that can affect loratadine. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

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Advair Diskus is used for long-term treatment of asthma and chronic obstructive pulmonary disease (COPD) in certain patients. It may also be used to treat other breathing conditions as determined by your doctor.

How Taken

Use Advair Diskus as directed by your doctor. Check the label on the medicine for exact dosing instructions.
Advair Diskus comes with an extra patient information sheet called a Medication Guide. Read it carefully. Read it again each time you get Advair Diskus refilled. Do not use a spacer with Advair Diskus.
Always ready and use this device in a level, flat position.
Hold the device in one hand and put the thumb of your other hand on the thumb grip. Push your thumb away from you as far as it will go until the mouthpiece appears and snaps into position.
Hold the device in a level, flat position with the mouthpiece toward you. Slide the lever away from you as far as it will go until it clicks.
Do NOT close or tilt the device, play with the lever, or move the lever more than 1 time. This may release or waste extra doses.
Hold the device away from your mouth and breathe out fully. Do NOT breathe into the inhaler. Put the mouthpiece to your lips. Breathe in quickly and deeply through the device.
Remove the device from your mouth. Hold your breath for about 10 seconds, or as long as is comfortable. Then breathe out slowly.
Close the device. Put your thumb on the thumb grip and slide it back toward you as far as it will go. The device will click shut and the lever will return to its original position.
Your dose of medicine is a very fine powder. Most, but not all, patients can taste or feel the dose. Do NOT use another dose if you do not taste or feel the medicine. If you are not sure if you are receiving your dose, contact your doctor or pharmacist.
Rinse your mouth with water after using Advair Diskus. DO NOT swallow the rinse solution. Spit the rinse water out.
If you are using other inhaled medicines, wait a few minutes between using Advair Diskus Powder and other inhalers, unless directed otherwise by your doctor.
Take your doses of Advair Diskus about 12 hours apart, unless your doctor tells you otherwise.
Never wash the mouthpiece or any other part of the inhaler. Keep it dry. Store Advair Diskus in a dry place.
Throw Advair Diskus Powder away 1 month after you remove it from the foil pouch, or after the dose indicator reads “0,” whichever comes first.
You may breathe more easily after the first dose of Advair Diskus. However, it may take 1 week or longer to achieve the most benefit.
Use Advair Diskus Powder on a regular schedule to get the most benefit from it. Using Advair Diskus at the same times each day will help you remember to use it. Do not stop using Advair Diskus even if you feel better unless your doctor tells you to.

Drug Class and Mechanism

Advair Diskus is a long-acting corticosteroid and bronchodilator combination. It works by reducing inflammation and widening the airways in the lungs, which helps you breath more easily.

Missed Dose

If you miss a dose of Advair Diskus, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Storage

Store Advair Diskus at room temperature, between 68 and 77 degrees F (20 and 25 degrees C), in a dry place. Store away from direct heat and sunlight, moisture, and light. The inhalation device is not reusable and should be discarded 1 month after removal from the moisture-protective foil overwrap pouch or after all blisters have been used, whichever comes first.

Warnings Precautions

Do NOT use Advair Diskus Powder if:

• you are allergic to any ingredient in Advair Diskus Powder or to milk proteins you are having an asthma attack (eg, sudden, severe onset or worsening of asthma symptoms such as chest tightness, cough, shortness of breath, wheezing)
• you are using another type of long-acting inhaled bronchodilator (eg, formoterol inhalation powder, salmeterol inhalation powder)
• you are taking an azole antifungal (eg, ketoconazole), certain HIV protease inhibitors (eg, ritonavir), a macrolide antibiotic (eg, clarithromycin), nefazodone, or telithromycin

Contact your doctor or health care provider right away if any of these apply to you.
Some medical conditions may interact with Advair Diskus Powder. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you are taking a monoamine oxidase inhibitor (MAOI) (eg, phenelzine) or tricyclic antidepressant (eg, amitriptyline), or if you have taken either of these medicines within the last 14 days
• if you have high blood acid levels (eg, ketoacidosis) or a history of diabetes, glaucoma, or increased pressure in the eye, heart problems (eg, fast or irregular heartbeat, heart blood vessel problems), high blood pressure, nervous system problems, liver problems, low blood potassium levels, seizures, thyroid problems, or an adrenal gland tumor
• if you are having a COPD flare-up, have recently been to an emergency room for asthma, have a history of frequent hospitalizations for asthma, or have ever had a life-threatening asthma attack
• if you have a fungal, bacterial, or parasitic infection; a viral infection (eg, measles, chickenpox, shingles); herpes virus infection of the eye; tuberculosis (TB); a history of a positive TB skin test; or immune system problems; or if you have had a recent vaccination
• if you have weak bones (osteoporosis) or have risk factors for osteoporosis (eg, a family history of osteoporosis, tobacco use, long-term use of corticosteroids or certain seizure medicines, limited physical exercise, poor nutrition)

Some MEDICINES MAY INTERACT with Advair Diskus Powder. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Diuretics (eg, hydrochlorothiazide, furosemide) or long-acting inhaled bronchodilators (eg, salmeterol inhalation powder, formoterol inhalation powder) because the risk of low blood potassium or irregular heartbeat may be increased
• Beta-blockers (eg, propranolol) because they may decrease Advair Diskus Powder’s effectiveness
• Azole antifungals (eg, ketoconazole), catechol-O-methyltransferase (COMT) inhibitors (eg, entacapone), delavirdine, HIV protease inhibitors (eg, ritonavir), macrolide antibiotics (eg, clarithromycin), MAOIs (eg, phenelzine), nefazodone, short-acting beta-agonist bronchodilators (eg, albuterol), telithromycin, or tricyclic antidepressants (eg, amitriptyline) because they may increase the risk of Advair Diskus Powder’s side effects

Possible Side Effects

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

• Diarrhea; dizziness; headache; mild muscle or bone pain; nausea; nervousness; throat irritation; tremor; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

• Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); behavior changes; blurred vision or other vision changes; chest pain; choking; fast or irregular heartbeat; hoarseness; numbness or tingling in hands or feet; seizures; severe muscle weakness, cramps, or spasms; severe or persistent bone pain; severe or persistent dizziness or headache; signs of infection (eg, fever, chills, persistent headache/sore throat, ear pain, increased mucus production or change in mucus color); swelling or tightness in the throat; trouble sleeping; unusual tiredness or weakness; vaginal odor or discharge; weight gain; white patches or sores on the tongue or mouth; worsening of asthma symptoms (eg, increased wheezing, coughing, chest tightness, shortness of breath).

More Information

Advair Discus is to be used only by the patient for whom it is prescribed. Do not share it with other people

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Cimetidine is in a group of drugs called histamine receptor antagonists. Cimetidine works by decreasing the amount of acid your stomach produces.

Cimetidine is used to treat and prevent certain types of ulcer, and to treat conditions that cause the stomach to produce too much acid. Cimetidine is also used to treat gastroesophageal reflux disease (GERD), when stomach acid backs up into the esophagus and causes heartburn.

Cimetidine may also be used for conditions other than those listed in this medication guide.

What is the most important information I should know about Tagamet (Cimetidine)?

Use this medication exactly as directed on the label, or as your doctor has prescribed it for you. Do not use more of the medication than recommended. Do not use the medication for longer than recommended.

Avoid taking antacids unless your doctor recommends them for heartburn pain. Follow your doctor’s advice about the type of antacid to use and when to use it. You may not be able to take the antacid at the same time you take your dose of cimetidine.

Taking cimetidine may make you more susceptible to virus that can cause pneumonia. This has occurred most often in elderly people and in those with diabetes, a weak immune system, or chronic lung disease. Before using cimetidine, tell your doctor if you have any of these conditions.

There may be other drugs that can affect cimetidine. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

What should I discuss with my healthcare provider before taking Tagamet (Cimetidine)?

Taking cimetidine may make you more susceptible to virus that causes pneumonia. You may be more likely to develop pneumonia if you have certain health problems.

Before using this medication, tell your doctor if you have:

• diabetes;
• asthma or a chronic lung disorder;
• a weak immune system;
• bone marrow suppression;
• kidney disease; or
• liver disease.

If you have any of the conditions listed above, you may not be able to use cimetidine or you may need a dosage adjustment or special tests during treatment.

Cimetidine is in the FDA pregnancy category B. This means that it is not expected to be harmful to an unborn baby. Do not use this medication without telling your doctor if you are pregnant or plan to become pregnant during treatment. Cimetidine passes into breast milk, and may be harmful to a nursing baby. Do not take cimetidine without telling your doctor if you are breast-feeding a baby. Do not give this medicine to a child younger than 16 years old unless your doctor has told you to.

How should I take Tagamet (Cimetidine)?

Use this medication exactly as directed on the label, or as your doctor has prescribed it for you. Do not use more of the medication than recommended. Do not use the medication for longer than recommended.

Cimetidine is usually taken with meals or at bedtime.

Take each dose with a full glass of water.

To be sure you get the correct dose of the oral solution (liquid), measure the liquid with a marked measuring spoon or medicine cup, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

Do not stop taking cimetidine without first talking to your doctor. It may take up to 8 weeks for an ulcer to heal.

Your ulcer may take longer to heal if you smoke cigarettes.

Store cimetidine at room temperature away from moisture, heat, and light.

What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine. Symptoms of a cimetidine overdose may include nausea, vomiting, diarrhea, confusion, extreme weakness, or fainting.

Tagamet (Cimetidine) side effects

Stop using cimetidine and get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

• cough, fever, chest congestion, trouble breathing;
• red or blistering skin rash;
• jaundice (yellowing of the skin or eyes);
• easy bruising or bleeding, unusual weakness;
• feeling faint, light-headed, disoriented, or confused;
• urinating less than usual;
• irregular heartbeat; or
• a rash.

Other less serious side effects are more likely to occur. Talk with your doctor if you have any of these side effects:

• feeling dizzy, depressed, or agitated;
• breast swelling or tenderness (in men);
• joint or muscle pain;
• mild skin rash;
• headache; or
• diarrhea, nausea, or constipation.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect Tagamet (Cimetidine)?

If you also take ketoconazole (Nizoral), take it at least 2 hours before you take cimetidine.

Before taking this medication, tell your doctor if you are using any of the following medicines:

• a blood thinner (warfarin or Coumadin);
• phenytoin (Dilantin);
• nifedipine (Adalat);
• metronidazole (Flagyl);
• propranolol (Inderal);
• chlordiazepoxide (Librium);
• lidocaine (Xylocaine);
• diazepam (Valium);
• theophylline (Theo-Dur, Slo-Bid, Bronkodyl); or
• depression or anxiety medication such as amitriptyline (Elavil), imipramine (Tofranil), clomipramine (Anafranil), desipramine (Norpramin), nortripytyline (Aventyl).

You may not be able to take cimetidine, or you may require a dosage adjustment or special monitoring during treatment if you are taking any of the medicines listed above.

There may be other drugs not listed that can affect cimetidine. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

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Ranitidine is used for treating certain conditions that cause your body to make too much stomach acid (e.g., Zollinger-Ellison syndrome). It is also used to treat ulcers of the small intestine that have not responded to other treatment.

How Taken

Use Ranitidine as directed by your doctor.

• Take Ranitidine by mouth with or without food.

Ask your health care provider any questions you may have about how to use Ranitidine.

Drug Class and Mechanism

Ranitidine is an H2-receptor blocker. It works by blocking the action of histamine in the stomach. This reduces the amount of acid the stomach makes. Reducing stomach acid helps to reduce heartburn, to heal irritation of the esophagus, and to heal ulcers of the stomach or intestines.

Missed Dose

If you miss a dose of Ranitidine and are using it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Storage

Store Ranitidine between 68 and 77 degrees F (20 and 25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Ranitidine out of the reach of children and away from pets.

Warnings Precautions

Do not use Ranitidine if:

• you are allergic to any ingredient in Ranitidine;
• you have a history of porphyria (a blood disease).

Contact your doctor or health care provider right away if any of these apply to you.

Some medical conditions may interact with Ranitidine . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have a history of kidney or liver problems
• if you have abnormal blood electrolyte levels or a history of irregular heartbeat.

Some MEDICINES MAY INTERACT with Ranitidine . Tell your health care provider if you are taking any other medicines, especially any of the following:

• Certain benzodiazepines (eg, midazolam), glipizide, or procainamide because the risk of their side effects may be increased by Ranitidine
• Certain HIV protease inhibitors (eg, atazanavir), dasatinib, delavirdine, gefitinib, itraconazole, or ketoconazole because their effectiveness may be decreased by Ranitidine

Possible Side Effects

Check with your doctor if any of these most common side effects persist or become bothersome:

• constipation; diarrhea; headache; nausea; stomach upset.

Seek medical attention right away if any of these severe side effects occur:

• severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); confusion; dark urine; fast, slow, or irregular heartbeat; fever, chills, or sore throat; hallucinations; severe or persistent headache or stomach pain; unusual bruising or bleeding; yellowing of the eyes or skin.

More Information

If you have any questions about Ranitidine, please talk with your doctor, pharmacist, or other health care provider.
Ranitidine is to be used only by the patient for whom it is prescribed. Do not share it with other people.

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Pepcid is in a group of drugs called histamine-2 blockers. It works by decreasing the amount of acid the stomach produces.

Pepcid is used to treat and prevent ulcers in the stomach and intestines. It also treats conditions in which the stomach produces too much acid, such as Zollinger-Ellison syndrome. Pepcid also treats gastroesophageal reflux disease (GERD) and other conditions in which acid backs up from the stomach into the esophagus, causing heartburn.

Pepcid may also be used for other purposes not listed in this medication guide.

Important information about Pepcid

You should not use Pepcid if you are allergic to famotidine or similar medications such as ranitidine (Zantac), cimetidine (Tagamet), or nizatidine (Axid).

Before taking Pepcid, tell your doctor if you have kidney or liver disease, stomach cancer or other problems, or asthma, COPD, or other breathing problems.

The famotidine orally disintegrating tablet (Pepcid RPD) may contain phenylalanine. Talk to your doctor before using this form of ranitidine if you have phenylketonuria (PKU).

Avoid taking cimetidine (Tagamet), ranitidine (Zantac), or nizatidine (Axid) while you are taking Pepcid, unless your doctor has told you to.

Pepcid can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Pepcid may be only part of a complete program of treatment that also includes changes in diet or lifestyle habits. Follow your doctor’s instructions very closely.

Heartburn can be confused with early symptoms of heart attack. Seek emergency medical attention if you have chest pain or heavy feeling, dizziness, pain spreading to the arm or shoulder, sweating, nausea or vomiting, and a general ill feeling.

Before taking Pepcid

Heartburn can be confused with early symptoms of heart attack. Seek emergency medical attention if you have chest pain or heavy feeling, dizziness, pain spreading to the arm or shoulder, sweating, nausea or vomiting, and a general ill feeling.

You should not use Pepcid if you are allergic to famotidine or similar medications such as ranitidine (Zantac), cimetidine (Tagamet), or nizatidine (Axid).

Before taking Pepcid, tell your doctor if you are allergic to any drugs, or if you have:

• kidney disease; or
• liver disease;
• stomach cancer or other problems; or
• asthma, chronic obstructive pulmonary disease (COPD), or other breathing problems.

If you have any of the conditions listed above, you may need a dose adjustment or special tests to safely take Pepcid.

The famotidine orally disintegrating tablet may contain phenylalanine. Talk to your doctor before using this form of ranitidine if you have phenylketonuria (PKU).

FDA pregnancy category B. This medication is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Pepcid can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I take Pepcid?

Use Pepcid exactly as directed on the label, or as prescribed by your doctor. Do not use it in larger amounts or for longer than recommended. Follow your doctor’s instructions.

The chewable tablet must be chewed thoroughly before swallowing.

Shake the oral suspension (liquid) for 5 to 10 seconds before you measure a dose. To be sure you get the correct dose, measure the liquid with a marked measuring spoon or medicine cup, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

To take famotidine orally disintegrating tablets (Pepcid RPD):

• Keep the tablet in its blister pack until you are ready to take the medicine. Open the package and peel back the foil from the tablet blister. Do not push a tablet through the foil or you may damage the tablet.
• Using dry hands, remove the tablet and place it on your tongue. It will begin to dissolve right away.
• Do not swallow the tablet whole. Allow it to dissolve in your mouth without chewing.
• Swallow several times as the tablet dissolves. If desired, you may drink liquid to help swallow the dissolved tablet.

Although most ulcers heal within 4 weeks of Pepcid treatment, it may take up to 8 weeks of using this medicine before your ulcer heals. For best results, keep using the medication as directed. Talk with your doctor if your symptoms do not improve after 6 weeks of treatment.

Pepcid may be only part of a complete program of treatment that also includes changes in diet or lifestyle habits. Follow your doctor’s instructions very closely.

Store Pepcid at room temperature away from moisture, heat, and light. Throw away any unused Pepcid liquid that is older than 30 days.

What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include nausea, vomiting, diarrhea, stomach pain, fast heart rate, or fainting.

Pepcid side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using Pepcid and call your doctor at once if you have a serious side effect such as:

• easy bruising or bleeding;
• fast or pounding heartbeat;
• confusion, hallucinations, seizure;
• numbness or tingly feeling; or
• jaundice (yellowing of the skin or eyes).

Less serious Pepcid side effects may include:

• nausea, vomiting, diarrhea, constipation;
• dry mouth;
• dizziness, weakness, mood changes;
• headache; or
• muscle cramps, joint pain.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect.

What other drugs will affect Pepcid?

Tell your doctor about all other medications you use, especially:

• atazanavir (Reyataz);
• itraconazole (Sporanox);
• ketoconazole (Nizoral); or
• aspirin or other NSAIDs (non-steroidal anti-inflammatory drugs) such as ibuprofen (Motrin, Advil), naproxen (Aleve, Naprosyn), diclofenac (Cataflam, Voltaren), etodolac (Lodine), indomethacin (Indocin), ketoprofen (Orudis), piroxicam (Feldene), and others.

This list is not complete and there may be other drugs that can interact with Pepcid. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.

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Metoclopramide increases muscle contractions in upper digestive tract. This speeds up the rate at which the stomach empties into the intestines.

Metoclopramide is used short-term to treat heartburn caused by gastroesophageal reflux in people who have used other medications without relief of symptoms.

Metoclopramide is also used to treat slow gastric emptying in people with diabetes (also called diabetic gastroparesis), which can cause nausea, vomiting, heartburn, loss of appetite, and a feeling of fullness after meals.

Metoclopramide may also be used for other purposes not listed in this medication guide.

Important information about metoclopramide

You should not take this medication if you are allergic to metoclopramide, or if you have bleeding or blockage in your stomach or intestines, epilepsy or other seizure disorder, or an adrenal gland tumor (pheochromocytoma).

Before taking metoclopramide, tell your doctor if you have kidney or liver disease, congestive heart failure, diabetes, or a history of depression.

Avoid drinking alcohol. It can increase some of the side effects of metoclopramide. There are many other medicines that can interact with metoclopramide. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor. Keep a list with you of all the medicines you use and show this list to any doctor or other healthcare provider who treats you. Stop using metoclopramide and call your doctor at once if you have tremors or uncontrolled muscle movements, fever, stiff muscles, confusion, sweating, fast or uneven heartbeats, rapid breathing, depressed mood, thoughts of suicide or hurting yourself, hallucinations, anxiety, agitation, seizure, or jaundice (yellowing of your skin or eyes). After you stop taking metoclopramide, you may have unpleasant withdrawal symptoms such as headache, dizziness, or nervousness. Talk to your doctor about how to avoid withdrawal symptoms when stopping the medication.

Before taking metoclopramide

You should not take this medication if you are allergic to metoclopramide, or if you have:

• bleeding or blockage in your stomach or intestines;
• a perforation (hole) in your stomach or intestines;
• epilepsy or other seizure disorder; or
• an adrenal gland tumor (pheochromocytoma).

Before taking metoclopramide, tell your doctor if you have

• kidney disease;
• liver disease (especially cirrhosis);
• congestive heart failure;
• diabetes (your insulin dose may need adjusting); or
• a history of depression.

If you have any of these conditions, you may need a dose adjustment or special tests to safely take metoclopramide.

FDA pregnancy category B. This medication is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Metoclopramide can pass into breast milk and may harm a nursing baby. Do not use metoclopramide without telling your doctor if you are breast-feeding a baby.

How should I take metoclopramide?

Take metoclopramide exactly as prescribed by your doctor. Do not take it in larger amounts or for longer than recommended. Follow the directions on your prescription label.

Take this medicine with a full glass of water.

Measure liquid medicine with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

The oral concentrate form of metoclopramide must be mixed with another liquid, such as water, fruit juice, soda, or a soft food like applesauce or pudding. Carefully follow mixing directions to make sure you get the correct dose.

Metoclopramide is usually taken before meals and at bedtime. Your doctor may want you to take the medication as needed only with meals that usually cause heartburn. Follow your doctor’s instructions.

Store metoclopramide at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to take the medicine and skip the missed dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine. Overdose symptoms may include drowsiness, confusion, tremors or uncontrolled muscle movements in face or neck, or seizure (convulsions).

Metoclopramide side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using metoclopramide and call your doctor at once if you have any of these serious side effects:

• tremors, or restless muscle movements in your eyes, tongue, jaw, or neck;
• mask-like appearance of the face;
• fever, stiff muscles, confusion, sweating, fast or uneven heartbeats, rapid breathing;
• depressed mood, thoughts of suicide or hurting yourself;
• hallucinations, anxiety, agitation, jittery feeling, trouble staying still;
• swelling, fluid retention;
• jaundice (yellowing of your skin or eyes); or
• seizure (convulsions).

Less serious side effects may include:

• feeling restless, drowsy, tired, or dizzy;
• headache, sleep problems (insomnia);
• nausea, diarrhea;
• breast tenderness or swelling;
• changes in your menstrual periods; or
• urinating more than usual.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect.

After you stop taking metoclopramide, you may have unpleasant withdrawal symptoms such as headache, dizziness, or nervousness. Talk to your doctor about how to avoid withdrawal symptoms when stopping the medication.

What other drugs will affect metoclopramide?

Before taking metoclopramide, tell your doctor if you are taking any of the following medicines:

• acetaminophen (Tylenol);
• cyclosporine (Gengraf, Neoral, Sandimmune);
• digoxin (digitalis, Lanoxin);
• glycopyrrolate (Robinul);
• levodopa (Larodopa, Atamet, Parcopa, Sinemet);
• mepenzolate (Cantil);
• tetracycline (Brodspec, Panmycin, Robitet, Sumycin, Tetracap, and others);
• atropine (Donnatal, and others), benztropine (Cogentin), dimenhydrinate (Dramamine), methscopolamine (Pamine), or scopolamine (Transderm-Scop);
• bladder or urinary medications such as darifenacin (Enablex), tolterodine (Detrol), or solifenacin (Vesicare);
• bronchodilators such as ipratroprium (Atrovent) or tiotropium (Spiriva);
• irritable bowel medications such as dicyclomine (Bentyl), hyoscyamine (Anaspaz, Cystospaz, Levsin), or propantheline (Pro-Banthine); or
• an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate).

This list is not complete and there may be other drugs that can interact with metoclopramide. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.

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Carafate (Sucralfate) is an anti-ulcer medication.

Carafate (Sucralfate) is not greatly absorbed into the body through the digestive tract. It works mainly in the lining of the stomach by adhering to ulcer sites and protecting them from acids, enzymes, and bile salts.

Carafate (Sucralfate) is used to treat an active duodenal ulcer. Sucralfate can heal an active ulcer, but it will not prevent future ulcers from occurring.

Sucralfate may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about Carafate (Sucralfate)?

Before taking sucralfate, tell your doctor if you have kidney disease (or if you are on dialysis). You may need a dose adjustment or special tests to safely take sucralfate. Take sucralfate on an empty stomach, at least 1 hour before or 2 hours after a meal. Take sucralfate for the full prescribed length of time. Your symptoms may improve before the ulcer is completely cleared.

Avoid taking any other medications at the same time you take sucralfate. It is best not to take other medicines within 2 hours before or after taking sucralfate.

Avoid using antacids without your doctor’s advice. Use only the specific type of antacid your doctor recommends. Antacids contain different medicines and some types can make it harder for sucralfate to work in your stomach.

If your doctor does recommend using an antacid, avoid taking it within 30 minutes before or after taking sucralfate.

What should I discuss with my healthcare provider before taking Carafate (Sucralfate)?

Before taking sucralfate, tell your doctor if you have kidney disease (or if you are on dialysis). You may need a dose adjustment or special tests to safely take sucralfate. FDA pregnancy category B. This medication is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether sucralfate passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I take Carafate (Sucralfate)?

Take this medication exactly as prescribed by your doctor. Do not take it in larger amounts or for longer than recommended. Follow the directions on your prescription label.

Take sucralfate with a full glass of water. Take sucralfate on an empty stomach, at least 1 hour before or 2 hours after a meal. Shake the oral suspension (liquid) well just before you measure a dose. To be sure you get the correct dose, measure the liquid with a marked measuring spoon or medicine cup, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one. Take this medication for the full prescribed length of time. Your symptoms may improve before the ulcer is completely cleared. Store sucralfate at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to take the medicine and skip the missed dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine.

An overdose of sucralfate is not likely to produce life-threatening symptoms.

Carafate (Sucralfate) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Less serious side effects may include:

• nausea, vomiting, indigestion;
• stomach pain;
• constipation, diarrhea;
• mild itching or skin rash;
• sleep problems (insomnia);
• dizziness, drowsiness, spinning sensation;
• headache; or
• back pain.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect.

What other drugs will affect Carafate (Sucralfate)?

Taking sucralfate can make it harder for your body to absorb many other medications, especially:

• cimetidine (Tagamet);
• digoxin (digitalis, Lanoxin);
• levothyroxine (Synthroid);
• phenytoin (Dilantin);
• quinidine (Quinaglute, Quinidex, Quin-Release);
• ranitidine (Zantac);
• tetracycline (Brodspec, Panmycin, Sumycin, Tetracap);
• theophylline (Elixophyllin, Respbid, Slo-Bid, Theo-Dur, and others);
• a blood thinner such as warfarin (Coumadin); or
• certain antibiotics such as ciprofloxacin (Cipro), levofloxacin (Levaquin), lomefloxacin (Maxaquin), ketoconazole (Nizoral), and others.

This list is not complete and there may be other drugs that can interact with sucralfate. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.

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Allopurinol is a xanthine oxidase inhibitor. It reduces the production of uric acid in your body. Uric acid buildup can lead to gout or kidney stones.

Allopurinol is used to treat gout. It is also used to treat patients with kidney stones and to decrease levels of uric acid in people who are receiving cancer treatment.

Allopurinol may also be used for other purposes not listed here.

Important information about Allopurinol

Do not use this medication if you have ever had a serious allergic reaction to allopurinol. Stop taking allopurinol and call your doctor at once if you have any signs of skin rash, no matter how mild. Take each dose with a full glass of water. To reduce your risk of kidney stones forming, drink 8 to 10 full glasses of fluid every day, unless your doctor tells you otherwise.

Allopurinol can lower the blood cells that help your body fight infections. This can make it easier for you to bleed from an injury or get sick from being around others who are ill. To be sure your blood cells do not get too low, your blood will need to be tested on a regular basis. Do not miss any scheduled appointments.

Avoid drinking alcohol. It can make your condition worse. Allopurinol can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Before taking Allopurinol

Do not use this medication if you have ever had a serious allergic reaction to allopurinol. Before taking allopurinol, tell your doctor if you are allergic to any drugs, or if you have:

• kidney disease;
• liver disease;
• diabetes;
• congestive heart failure;
• high blood pressure; or
• if you are receiving any chemotherapy.

If you have any of these conditions, you may need a dose adjustment or special tests to safely take allopurinol.

FDA pregnancy category C. Allopurinol may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Allopurinol can pass into breast milk and may harm a nursing baby. Do not use allopurinol without telling your doctor if you are breast-feeding a baby.

How should I take Allopurinol?

Take allopurinol exactly as it was prescribed for you. Do not take allopurinol in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.

Your doctor may occasionally change your dose to make sure you get the best results from allopurinol.

Take each dose with a full glass of water. To reduce your risk of kidney stones forming, drink 8 to 10 full glasses of fluid every day, unless your doctor tells you otherwise.

Allopurinol can lower the blood cells that help your body fight infections. This can make it easier for you to bleed from an injury or get sick from being around others who are ill. To be sure your blood cells do not get too low, your blood will need to be tested on a regular basis. Your kidney or liver function may also need to be tested. Do not miss any scheduled appointments.

Store allopurinol at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the allopurinol dose at your next regularly scheduled time. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much allopurinol.

An overdose of allopurinol is not expected to produce life-threatening symptoms.

Allopurinol side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using allopurinol and call your doctor at once if you have any of these serious side effects:

• the first sign of any skin rash, no matter how mild;
• pain or bleeding when you urinate;
• urinating less than usual or not at all;
• fever, sore throat, and headache with a severe blistering, peeling, and red skin rash;
• bruising, severe tingling, numbness, pain, muscle weakness;
• easy bruising or bleeding, unusual weakness;
• fever, chills, body aches, flu symptoms;
• jaundice (yellowing of the skin or eyes); or
• seizure (convulsions).

Less serious side effects may include:

• nausea, vomiting, diarrhea;
• dizziness or drowsiness;
• increased sweating; or
• joint pain.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect.

What other drugs will affect Allopurinol?

Before taking allopurinol, tell your doctor if you are using any of the following drugs:

• azathioprine (Imuran);
• chlorpropamide (Diabinese);
• cyclosporine (Gengraf, Sandimmune, Neoral);
• mercaptopurine (Purinethol);
• an antibiotic such as ampicillin (Principen, Omnipen, others) or amoxicillin (Amoxil, Augmentin, Trimox, Wymox);
• a blood thinner such as dicoumarol or warfarin (Coumadin); or
• a diuretic (water pill).

This list is not complete and there may be other drugs that can interact with allopurinol. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

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