Cystone naturally promotes a healthy urinary tract and helps maintain normal urine composition and mucosal integrity. It is a natural aid in maintaining healthy water management, and a diuretic that relieves temporary water – weight gain. As a dietary supplement, Cystone assists kidneys and urinary tract in normal functions. It provides normal absorption and utilization for overall healthy urinary tract.
How Taken
In urolithiasis & crystalluria: 2 capsules twice daily for four to six months or till the stone(s) passes out. In urinary infections: 1 capsules twice daily until the infection is cleared. In acute renal colic: The dose may be increased to 2 capsules thrice daily. In burning micturition: 1 capsule twice daily for 4 to 5 days. To prevent recurrence of renal stones: 1 capsule twice daily for 4 to 6 months every year, more particularly during summer months. Allow several weeks for benefits. The use of natural products provides progressive but long-lasting results.
Drug Class and Mechanism
Cystone prevents supersaturation of lithogenic substances, controls oxamide (a substance that precipitates stone formation) absorption from the intestine and corrects the crystalloid-colloid imbalance. Cystone inhibits calculogenesis by reducing stone-forming substances like oxalic acid, calcium hydroxyproline, and causes their expulsion by micropulverization. Cystone causes disintegration of the calculi and the crystals by acting on the mucin, which binds the particles together.
Missed Dose
If you miss a dose of this medicine and you are using it regularly, take it as soon as possible. Do not take 2 doses at once.
Storage
Store at the room temperature away from moisture and sunlight. Keep out of the reach of children.
Warnings Precautions
No absolute contraindications.
Possible Side Effects
Cystone is not known to have any side effects if taken as per the prescribed dosage.
More Information
Cystone has been scientifically validated by many clinical studies. Its formula has been subjected to the modern scrutiny of clinical testing to prove its benefits in gently addressing your health concerns, and its quality is controlled by the most sophisticated chromatographic “fingerprinting” techniques.
Detrol is used to treat overactive bladder with symptoms of urinary frequency, urgency, and incontinence.
Detrol may also be used for other purposes not listed in this medication guide.
Important information about Detrol (Tolterodine)
Do not take Detrol if you are allergic to tolterodine, if you have uncontrolled glaucoma, or if you have a blockage of the urinary tract, stomach, or intestines.
Before taking Detrol, tell your doctor if you have a personal or family history of “Long QT syndrome.”
Do not crush, chew, break, or open a controlled-release capsule. Swallow the pill whole. It is specially made to release medicine slowly in the body. Breaking or opening the pill would cause too much of the drug to be released at one time. Detrol can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert. Avoid drinking alcohol. It can increase some of the side effects of Detrol. There are many other medicines that can interact with Detrol. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor. Keep a list with you of all the medicines you use and show this list to any doctor or other healthcare provider who treats you.
Before taking Detrol (Tolterodine)
Do not take Detrol if you are allergic to tolterodine or if you have:
a blockage of the urinary tract (difficulty urinating);
a blockage in your stomach or intestines; or
untreated or uncontrolled glaucoma.
Before taking Detrol, tell your doctor if you are allergic to any drugs, or if you have:
liver disease;
kidney disease;
glaucoma; or
a personal or family history of “Long QT syndrome.”
If you have any of these conditions, you may need a dose adjustment or special tests to safely take Detrol.
FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether Detrol passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
How should I take Detrol (Tolterodine)?
Take Detrol exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.
Your doctor may occasionally change your dose to make sure you get the best results from this medication.
Take this medication with a full glass of water. Do not crush, chew, break, or open a controlled-release capsule. Swallow the pill whole. It is specially made to release medicine slowly in the body. Breaking or opening the pill would cause too much of the drug to be released at one time. Store Detrol at room temperature away from moisture and heat.
What happens if I miss a dose?
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention if you think you have used too much of this medication.
Overdose symptoms may include dry mouth, blurred vision, and fast heartbeat.
Detrol (Tolterodine) side effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using Detrol and call your doctor at once if you have any of these serious side effects:
chest pain, fast or uneven heart rate;
feeling short of breath, even with mild exertion;
swelling, rapid weight gain;
confusion, hallucinations;
urinating less than usual or not at all; or
painful or difficult urination.
Less serious side effects may include:
dry mouth, dry eyes;
blurred vision;
dizziness, drowsiness;
constipation or diarrhea;
stomach pain or upset;
joint pain; or
headache.
This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect.
What other drugs will affect Detrol (Tolterodine)?
Before taking Detrol, tell your doctor if you are using any of the following drugs:
arsenic trioxide (Trisenox);
bepridil (Vascor),
cisapride (Propulsid);
chloroquine (Arelan) or halofantrine (Halfan);
cyclosporine (Gengraf, Neoral, Sandimmune);
droperidol (Inapsine);
narcotic medication such as levomethadyl (Orlaam); or methadone (Dolophine, Methadose);
medicines to treat psychiatric disorder, such as chlorpromazine (Thorazine), haloperidol (Haldol), mesoridazine (Serentil) pimozide (Orap), or thioridazine (Mellaril); or
heart rhythm medicine such as amiodarone (Cordarone, Pacerone), dofetilide (Tikosyn), disopyramide (Norpace), procainamide (Procan, Pronestyl), quinidine (Cardioquin, Quinaglute), or sotalol (Betapace).
This list is not complete and there may be other drugs that can interact with Detrol. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.
Levothyroxine is a replacement for a hormone that is normally produced by your thyroid gland to regulate the body’s energy and metabolism. Levothyroxine is given when the thyroid does not produce enough of this hormone on its own.
Levothyroxine treats hypothyroidism (low thyroid hormone). Levothyroxine is also used to treat or prevent goiter (enlarged thyroid gland), which can be caused by hormone imbalances, radiation treatment, surgery, or cancer.
Levothyroxine should not be used to treat obesity or weight problems.
Levothyroxine may also be used for other purposes not listed in this medication guide.
What is the most important information I should know about Synthroid (Levothyroxine)?
Since thyroid hormone occurs naturally in the body, almost anyone can take levothyroxine. You should not use this medication if you have had a heart attack, a thyroid disorder called thyrotoxicosis, or an adrenal gland problem that is not controlled by treatment.
Before taking this medication, tell your doctor if you have heart disease, coronary artery disease, anemia (lack of red blood cells), diabetes, problems with your pituitary or adrenal glands, or a history of blood clots.
If you use insulin or take diabetes medicine by mouth, ask your doctor if your dose needs to be changed when you start using levothyroxine.
Different brands of levothyroxine may not work the same. If you get a prescription refill and your new pills look different, talk with your pharmacist or doctor.
It may take several weeks before your body starts to respond to this medication. Do not stop taking this medication suddenly. Even if you feel well, you may still need to take this medicine every day for the rest of your life to replace the thyroid hormone your body cannot produce.
There are many other medicines that can affect levothyroxine. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.
What should I discuss with my healthcare provider before taking Synthroid (Levothyroxine)?
Since thyroid hormone occurs naturally in the body, almost anyone can take levothyroxine. You should not use this medication if you have had a heart attack, a thyroid disorder called thyrotoxicosis, or an adrenal gland problem that is not controlled by treatment.
Before taking this medication, tell your doctor if you have heart disease, coronary artery disease, anemia (lack of red blood cells), diabetes, problems with your pituitary or adrenal glands, or a history of blood clots.
If you use insulin or take diabetes medicine by mouth, ask your doctor if your dose needs to be changed when you start using levothyroxine.
Levothyroxine is in the FDA pregnancy category A. This means that it is safe to use while you are pregnant. It is also safe to use while you are breast-feeding a baby. This drug does pass into breast milk, but it is not expected to be harmful to a nursing infant.
Tell your doctor if you become pregnant during treatment. You may need to increase your dose during pregnancy or if you plan to breast-feed.
In most cases, you will need to take levothyroxine for the rest of your life. Taking levothyroxine over long periods of time may cause bone loss, which can lead to osteoporosis. Talk with your doctor about how this could affect you.
How should I take Synthroid (Levothyroxine)?
Take levothyroxine exactly as your doctor has prescribed it for you. Do not use more of the medication than recommended. Do not take levothyroxine for longer than your doctor has prescribed.
Your doctor may occasionally change your dose to make sure you get the best results from this medication.
It is very important to take levothyroxine with a full glass (8 ounces) of water. The levothyroxine tablet can dissolve very quickly and swell in the throat, possibly causing choking or gagging. Take this medicine on an empty stomach, 30 minutes before eating. Levothyroxine is usually taken in the morning. Follow your doctor’s dosing instructions and try to take this medication at the same time each day.
It may take several weeks before your body starts to respond to this medication. Do not stop taking this medication suddenly. Even if you feel well, you may still need to take this medicine every day for the rest of your life to replace the thyroid hormone your body cannot produce.
To be sure this medication is helping your condition, your blood will need to be tested on a regular basis. Your kidney or liver function may also need to be tested. It is important that you not miss any scheduled visits to your doctor.
Tell any doctor or dentist who treats you that you are using levothyroxine.
Store levothyroxine at room temperature away from moisture and heat.
What happens if I miss a dose?
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention if you think you have used too much of this medicine.
Overdose symptoms may include chest pain, pounding heartbeat, tremor, shortness of breath, leg cramps, confusion, vomiting, diarrhea, or seizures.
Synthroid (Levothyroxine) side effects
Stop using levothyroxine and get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have any of these serious side effects:
headache;
sleep problems (insomnia);
nervous or irritable feeling;
fever, hot flashes, sweating;
changes in your menstrual periods;
appetite changes, weight changes;
Less serious side effects may include mild hair loss.
This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect.
What other drugs will affect Synthroid (Levothyroxine)?
The following drugs may cause medical problems if you use them with levothyroxine: lithium, amiodarone, or antidepressants. Tell your doctor if you have recently received radiation therapy with iodine (such as I-131).
This list is not complete and there are many other drugs that can interact with levothyroxine. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.
Certain medicines can be continued, but they may make levothyroxine less effective if taken at the same time. If you use any of the following drugs, use them at least 4 hours before or 4 hours after you take levothyroxine:
calcium carbonate (Caltrate, Citracal, Oystercal, and others);
ferrous sulfate iron supplement;
sucralfate (Carafate);
sodium polystyrene sulfonate (Kayexalate, Kionex, and others);
antacids that contain aluminum (Amphojel, Gaviscon, Maalox, Mylanta, Riopan, Rulox, Tums, and others); and
cholesterol-lowering drugs cholestyramine (Questran) and colestipol (Colestid).
Albuterol and ipratropium are bronchodilators that relax muscles in the airways and increase air flow to the lungs.
Combivent is used to prevent bronchospasm in people with chronic obstructive pulmonary disease (COPD) who are also using other medicines to control their condition.
Combivent may also be used for other purposes not listed in this medication guide.
Important information about Combivent (Albuterol and Ipratropium)
Do not use Combivent if you are allergic to soybeans, peanuts, or other food products that contain soya lecithin.
Call your doctor right away if you feel that this medicine is not working as well as usual, or if it makes your condition worse. If it seems like you need to use more of any of your medications in a 24-hour period, talk with your doctor.
Extreme heat can cause the medicine canister to burst. Do not store your inhaler in your car on hot days. Do not throw an empty canister into open flame.
Before using Combivent (Albuterol and Ipratropium)
Do not use Combivent if you are allergic to soybeans, peanuts, or other food products that contain soya lecithin.
Before using Combivent, tell your doctor if you have:
heart disease, high blood pressure, or congestive heart failure;
a seizure disorder such as epilepsy;
diabetes;
overactive thyroid;
glaucoma;
an enlarged prostate or problems with urination; or
liver or kidney disease.
If you have any of these conditions, you may need a dose adjustment or special tests to safely take Combivent.
FDA pregnancy category C. Combivent may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether Combivent passes into breast milk or if it could harm a nursing baby. Do not use Combivent without telling your doctor if you are breast-feeding a baby.
How should I use Combivent (Albuterol and Ipratropium)?
Use Combivent exactly as it was prescribed for you. Do not use the medication in larger amounts, or use it for longer than recommended by your doctor. Follow the instructions on your prescription label.
Combivent may increase the risk of asthma-related death. It is critical that you use only the prescribed dose of this medicine and follow all patient instructions for safe use of the medication.
Combivent comes with patient instructions for safe and effective use. Follow these directions carefully. Ask your doctor or pharmacist if you have any questions.
When using the inhaler device for the first time, prime it by spraying 2 test sprays into the air, away from your face. Also prime the inhaler if you have not used it for 3 days or longer.
The instructions below are for standard use of the inhaler and nebulizer devices. Your doctor may want you to use your device differently. Be sure you understand all instructions that are specific to your use of Combivent.
To use the inhaler:
Shake the canister vigorously for at least 10 seconds before each spray.
Uncap the mouthpiece of the inhaler. Breathe out fully. Put the mouthpiece into your mouth and close your lips. Keep your eyes closed to prevent spraying any medicine into your eyes. Breathe in slowly while pushing down on the canister. Hold your breath for 10 seconds, then breathe out slowly.
If you use more than one inhalation at a time, wait at least 2 minutes before using the second inhalation.
Keep your inhaler clean and dry, and store it with the cap on the mouthpiece. Clean your inhaler once a week by removing the canister and placing the mouthpiece under warm running water for at least 30 seconds. Allow the parts to dry before putting the inhaler back together.
To use the solution with a nebulizer:
Measure the correct amount of medicine using the dropper provided, or use the proper number of ampules. Place the liquid into the medication chamber of the nebulizer. If using a medicine dropper, do not allow the dropper to touch any surface including your hands or the nebulizer.
Attach the mouthpiece or face mask to the drug chamber. Then, attach the drug chamber to the compressor. Sit upright in a comfortable position. Place the mouthpiece into your mouth or put the face mask on, covering your nose and mouth. Breathe in slowly and evenly until you have inhaled all of the medicine (usually 5 to 15 minutes). The treatment is complete when no more mist is formed by the nebulizer and the drug chamber is empty.
Clean the nebulizer after each use. Follow the cleaning directions that came with your nebulizer.
Call your doctor right away if you feel that this medicine is not working as well as usual, or if it makes your condition worse. If it seems like you need to use more of any of your medications in a 24-hour period, talk with your doctor.
To be sure Combivent is helping your condition, your lung function will need to be tested on a regular basis. It is important that you not miss any scheduled visits to your doctor.
It is important to use Combivent regularly to get the most benefit. Get your prescription refilled before you run out of medicine completely. Keep using all of your other medications as prescribed by your doctor.
Store Combivent at room temperature away from moisture and heat. Extreme heat can cause the medicine canister to burst. Do not store it in your car on hot days. Do not throw an empty canister into open flame.
Keep track of the number of sprays you have used and throw away the inhaler canister after 200 sprays, even if it feels like there is still medicine in it.
What happens if I miss a dose?
Use the medication as soon as you remember. If it is almost time for the next dose, skip the missed dose and use the medicine at the next regularly scheduled time. Do not use extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention if you think you have used too much of this medicine. An overdose of Combivent can be fatal. Overdose symptoms may include chest pain or heavy feeling, rapid or uneven heart rate, pain spreading to the arm or shoulder, nausea, sweating, weakness, or general ill feeling.
Combivent (Albuterol and Ipratropium) side effects
Stop using Combivent and get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using Combivent and call your doctor at once if you have any of these serious side effects:
bronchospasm (wheezing, chest tightness, trouble breathing), especially after starting a new canister of this medicine;
chest pain and fast, pounding, or uneven heart beats;
a beta-blocker such as acebutolol (Sectral), atenolol (Tenormin), carvedilol (Coreg), metoprolol (Lopressor), or propranolol (Inderal);
a stimulant, ADHD medication, diet pills, or over-the-counter cold or allergy medicines;
a diuretic (water pill) such as furosemide (Lasix), bumetanide (Bumex), ethacrynic acid (Edecrin), torsemide (Demadex), hydrochlorothiazide (Hydrodiuril), chlorthalidone (Hygroton, Thalitone), or chlorothiazide (Diuril); or
an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate).
This list is not complete and there may be other drugs that can interact with Combivent. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.
Atrovent is used to prevent bronchospasm, or narrowing airways in the lungs, in people with bronchitis, emphysema, or COPD (chronic obstructive pulmonary disease).
Atrovent may also be used for other purposes not listed in this medication guide.
What is the most important information I should know about Atrovent (Ipratropium)?
Before using this medication, tell your doctor if you have narrow-angle glaucoma, or an enlarged prostate or bladder obstruction. If you have any of these conditions, you may need a dose adjustment or special tests to safely use Atrovent.
Atrovent is used to prevent bronchospasm attacks. Atrovent will not treat bronchospasm while it is happening. You may still have difficulty breathing and may need to use one of your other medicines to treat the attack. To best control your condition, use Atrovent regularly, and continue using all your other medicines as directed by your doctor.
Use this medication exactly as it was prescribed for you. Do not use it in larger doses or for longer than recommended by your doctor.
Call your doctor right away if you feel that this medicine is not working as well as usual, or if it makes your condition worse. If it seems like you need to use more of any of your medications in a 24-hour period, talk with your doctor.
Extreme heat can cause the Atrovent canister to burst. Do not store your inhaler in your car on hot days. Do not throw an empty canister into open flame.
Keep track of the number of sprays you have used and throw away the inhaler canister after 200 sprays, even if it feels like there is still medicine in it.
What should I discuss with my healthcare provider before using Atrovent (Ipratropium)?
Atrovent is used to prevent bronchospasm attacks. This medication will not treat bronchospasm while it is happening. You may still have difficulty breathing and may need to use one of your other medicines to treat the attack. To best control your condition, use Atrovent regularly, and continue using all your other medicines as directed by your doctor.
Before using Atrovent, tell your doctor if you have:
narrow-angle glaucoma; or
an enlarged prostate or a bladder obstruction.
If you have any of these conditions, you may need a dose adjustment or special tests to safely use this medication.
FDA pregnancy category B: This medication is not expected to be harmful to an unborn baby. Do not use Atrovent without telling your doctor if you are pregnant or plan to become pregnant during treatment. It is not known if ipratropium passes into breast milk or if it could harm a nursing baby. Do not use Atrovent without telling your doctor if you are breast-feeding a baby. Atrovent should not be used by a child younger than 12 years of age.
How should I use Atrovent (Ipratropium)?
Use this medication exactly as it was prescribed for you. Do not use it in larger doses or for longer than recommended by your doctor.
This medication comes with patient instructions for safe and effective use. Follow these directions carefully. Ask your doctor or pharmacist if you have any questions.
When using the inhaler device for the first time, prime it by spraying 2 test sprays into the air, away from your face. Also prime the inhaler if you have not used it for 3 days or longer.
The instructions below are for standard use of the inhaler and nebulizer devices. Your doctor may want you to use your device differently. Be sure you understand all instructions that are specific to your use of Atrovent.
To use the inhaler:
Uncap the mouthpiece of the inhaler. Breathe out fully. Put the mouthpiece into your mouth and close your lips. Keep your eyes closed to prevent spraying any medicine into your eyes. Breathe in slowly while pushing down on the canister. Hold your breath for 10 seconds, then breathe out slowly.
If you use more than one inhalation at a time, wait at least 15 seconds before using the second inhalation.
Keep your inhaler clean and dry, and store it with the cap on the mouthpiece. Clean your inhaler once a week by removing the canister and placing the mouthpiece under warm running water for at least 30 seconds. Allow the parts to dry before putting the inhaler back together.
To use the solution with a nebulizer:
Measure the correct amount of medicine using the dropper provided, or use the proper number of ampules. Place the liquid into the medication chamber of the nebulizer. If using a medicine dropper, do not allow the dropper to touch any surface including your hands or the nebulizer.
Attach the mouthpiece or face mask to the drug chamber. Then, attach the drug chamber to the compressor. Sit upright in a comfortable position. Place the mouthpiece into your mouth or put the face mask on, covering your nose and mouth. Breathe in slowly and evenly until you have inhaled all of the medicine (usually 5 to 15 minutes). The treatment is complete when no more mist is formed by the nebulizer and the drug chamber is empty.
Clean the nebulizer after each use. Follow the cleaning directions that came with your nebulizer.
Call your doctor right away if you feel that this medicine is not working as well as usual, or if it makes your condition worse. If it seems like you need to use more of any of your medications in a 24-hour period, talk with your doctor.
To be sure this medication is helping your condition, your lung function will need to be tested on a regular basis. It is important that you not miss any scheduled visits to your doctor.
Store Atrovent at room temperature away from moisture and heat. Extreme heat can cause the canister to burst. Do not store it in your car on hot days. Do not throw an empty canister into open flame.
Keep track of the number of sprays you have used and throw away the inhaler canister after 200 sprays, even if it feels like there is still medicine in it.
What happens if I miss a dose?
Use the medication as soon as you remember. If it is almost time for the next dose, skip the missed dose and wait until your next regularly scheduled dose. Do not use extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention if you think you have used too much of this medicine. Atrovent is not expected to cause overdose symptoms.
Atrovent (Ipratropium) side effects
Stop using Atrovent and get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have a fast, pounding heartbeat.
Other less serious side effects are more likely to occur, such as:
headache, dizziness;
dry mouth, cough, hoarseness;
nausea, upset stomach; or
blurred vision.
If you switch from Atrovent to Atrovent HFA, you may notice a slightly different taste or feel after inhaling the medication.
This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect.
What other drugs will affect Atrovent (Ipratropium)?
Before using Atrovent, tell your doctor if you are using any of the following medicines:
atropine (Donnatal, and others),
belladonna,
clidinium (Quarzan),
dicyclomine (Bentyl),
glycopyrrolate (Robinul),
hyoscyamine (Anaspaz, Cystospaz, Levsin, and others)
mepenzolate (Cantil),
methantheline (Provocholine),
methscopolamine (Pamine), and
propantheline (Pro-Banthine), or
scopolamine (Transderm-Scop).
This list is not complete and there may be other drugs not listed that can affect Atrovent. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.
Topiramate is a seizure medication, also called an anticonvulsant.
Topiramate is used alone or in combination with other medications to prevent seizures in adults and children who are at least 2 years old.
Topiramate is also used to prevent migraine headaches. Topiramate will only prevent migraine headaches or reduce the number of attacks. It will not treat a headache that has already begun.
Topiramate may also be used for other purposes not listed in this medication guide.
What is the most important information I should know about Topamax (Topiramate)?
Seek emergency medical attention if you have a sudden change in vision and pain around or behind the eyes. These may be early signs of a serious side effect of topiramate. Do not stop taking topiramate without first talking to your doctor, even if you feel better. You may have increased seizures if you stop taking topiramate suddenly. You will need to use less and less before you stop the medication completely. Contact your doctor if your seizures get worse or you have them more often while taking topiramate.
You may have thoughts about suicide while taking this medication. Your doctor will need to check you at regular visits. Do not miss any scheduled appointments.
Call your doctor at once if you have any new or worsening symptoms such as: mood or behavior changes, depression, anxiety, or if you feel agitated, hostile, restless, hyperactive (mentally or physically), or have thoughts about suicide or hurting yourself. Carry an ID card or wear a medical alert bracelet stating that you are taking topiramate, in case of emergency. Any doctor, dentist, or emergency medical care provider who treats you should know that you are taking a seizure medication. Topiramate can cause side effects that may impair your vision or reactions. Be careful if you drive or do anything that requires you to be alert and able to see clearly. Avoid drinking alcohol. It can increase some of the side effects of topiramate, and can also increase the risk of a seizure.
Ketogenic or “ketosis” diets that are high in protein and low in carbohydrates can increase the risk of kidney stones. Avoid the use of such diets while you are taking topiramate.
What should I discuss with my healthcare provider before taking Topamax (Topiramate)?
Do not use this medication if you are allergic to topiramate.
Before taking topiramate, tell your doctor if you are allergic to any drugs, or if you have:
kidney disease or a history of kidney stones;
liver disease;
glaucoma;
asthma, emphysema, or bronchitis; or
if you have recently had surgery.
FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.
You may have thoughts about suicide while taking this medication. Tell your doctor if you have new or worsening depression or suicidal thoughts during the first several months of treatment, or whenever your dose is changed.
Your family or other caregivers should also be alert to changes in your mood or symptoms. Your doctor will need to check you at regular visits. Do not miss any scheduled appointments.
Topiramate can make birth control pills less effective. Talk with your doctor about other forms of birth control if you are trying to prevent pregnancy while taking topiramate. It is not known whether topiramate passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
How should I take Topamax (Topiramate)?
Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results from this medication.
Topiramate can be taken with or without food.
Take the medicine with a full glass of water.
The topiramate tablet should be swallowed whole. It has a bitter taste when chewed or broken.
To make the topiramate capsule easier to swallow, you may open the capsule and sprinkle the medicine into a spoonful of applesauce, custard, ice cream, oatmeal, pudding, or yogurt. Swallow this mixture right away without chewing. Do not save the mixture for later use.
To be sure this medication is not causing harmful effects, your blood will need to be tested on a regular basis. Your kidney or liver function may also need to be tested. Do not miss any scheduled visits to your doctor.
If you need to have any type of surgery, tell the surgeon ahead of time that you are using topiramate. You may need to stop using the medicine for a short time.
Do not stop taking topiramate without first talking to your doctor, even if you feel better. You may have increased seizures if you stop taking topiramate suddenly. You will need to use less and less before you stop the medication completely. Contact your doctor if your seizures get worse or you have them more often while taking topiramate. Carry an ID card or wear a medical alert bracelet stating that you are taking topiramate, in case of emergency. Any doctor, dentist, or emergency medical care provider who treats you should know that you are taking a seizure medication. Drink extra fluids each day while you are taking topiramate. This will lower your risk of having kidney stones or an electrolyte imbalance. Vomiting or diarrhea can lead to dehydration and cause an electrolyte imbalance. Call your doctor if you have ongoing vomiting or diarrhea while taking topiramate. Store topiramate at room temperature away from moisture and heat.
What happens if I miss a dose?
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at your next regularly scheduled time. Do not take extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical treatment if you think you have used too much of this medicine.
Overdose symptoms may include drowsiness, dizziness, agitation or depression, blurred vision, problems with speech or balance, stomach pain, chest pain, fast or pounding heartbeats, feeling light-headed, fainting, and seizure (convulsions).
Topamax (Topiramate) side effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any new or worsening symptoms such as: mood or behavior changes, depression, anxiety, or if you feel agitated, hostile, restless, hyperactive (mentally or physically), or have thoughts about suicide or hurting yourself.
Stop taking topiramate and call your doctor at once if you have any of these serious side effects:
sudden vision loss, pain around or behind your eyes;
dry mouth, increased thirst, confusion, drowsiness, decreased sweating, increased body temperature, and hot, dry skin,
nausea, vomiting, increased urination, muscle pain or weakness, fast heart rate, feeling light-headed, fainting, or seizure (convulsions); or
severe pain in your side or lower back, painful or difficult urination.
methscopolamine (Pamine) or scopolamine (Transderm-Scop);
risperidone (Risperdal);
bladder or urinary medications such as darifenacin (Enablex), oxybutynin (Ditropan, Oxytrol), tolterodine (Detrol), or solifenacin (Vesicare);
bronchodilators such as ipratropium (Atrovent) or tiotropium (Spiriva);
diabetes medicine you take by mouth, such as pioglitazone (Actos) or metformin (Actoplus Met, Avandamet, Glucophage, Fortamet);
glaucoma medications such as acetazolamide (Diamox), methazolamide (Neptazane), or dichlorphenamide (Daranide);
irritable bowel medications such as dicyclomine (Bentyl), hyoscyamine (Anaspaz, Cystospaz, Levsin, and others), propantheline (Pro-Banthine); or
other seizure medications such as carbamazepine (Carbatrol, Tegretol), lamotrigine (Lamictal), phenytoin (Dilantin), or valproic acid (Depakote, Depakene).
This list is not complete and there may be other drugs that can interact with topiramate. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.
Oxybutynin reduces muscle spasms of the bladder and urinary tract.
Oxytrol is used to treat symptoms of overactive bladder, such as frequent or urgent urination, incontinence (urine leakage), and increased nighttime urination.
Oxytrol may also be used for purposes other than those listed in this medication guide.
What is the most important information I should know about Oxytrol?
Do not use Oxytrol if you are allergic to oxybutynin, or if you have uncontrolled glaucoma, a blockage in your stomach or intestines, or if you are unable to urinate. Oxybutynin can cause blurred vision, drowsiness, or dizziness. Be careful if you drive or do anything that requires you to be alert and able to see clearly. Avoid drinking alcohol. It can increase some of the side effects of oxybutynin.
Avoid becoming overheated or dehydrated during exercise and in hot weather. Drink plenty of fluids to keep yourself hydrated while you are using oxybutynin.
Do not expose the Oxytrol patch to sunlight. It should be worn under clothing.
What should I discuss with my healthcare provider before using Oxytrol?
Do not use Oxytrol if you are allergic to oxybutynin, or if you have:
untreated or uncontrolled glaucoma;
a blockage in your digestive tract (stomach or intestines); or
if you have decreased urination or are unable to urinate.
Before using Oxytrol, tell your doctor if you are allergic to any drugs, or if you have:
glaucoma;
liver disease;
kidney disease;
myasthenia gravis;
an enlarged prostate;
an intestinal disorder, such as ulcerative colitis; or
a stomach disorder such as gastroesophageal reflux disease (GERD) or slow digestion.
If you have any of these conditions, you may not be able to use Oxytrol, or you may need a dosage adjustment or special tests during treatment.
FDA pregnancy category B. Oxytrol is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether Oxytrol passes into breast milk or if it could harm a nursing baby. Do not use Oxytrol without telling your doctor if you are breast-feeding a baby.
How should I use Oxytrol?
Use this medication exactly as it was prescribed for you. Do not use the medication in larger amounts, or use it for longer than recommended by your doctor. Follow the instructions on your prescription label.
Oxytrol comes with patient instructions for safe and effective use. Follow these directions carefully. Ask your doctor or pharmacist if you have any questions.
To use the Oxytrol patch, open the sealed pouch and remove the protective liner. Apply the Oxytrol transdermal patch to a clean, dry area on your stomach, hip or buttock. Avoid skin that is oily, irritated, or damaged. Avoid placing the Oxytrol patch on a skin area that will be rubbed by a waistband or tight clothing.
Press the Oxytrol patch onto the skin and press it down firmly with your fingers. Make sure the patch is well sealed around the edges. When properly applied, the patch should stay on while swimming or bathing.
Leave the Oxytrol patch in place and wear it for 3 to 4 days. You should change the patch twice per week. Each time you apply a new patch, choose a different skin area on your stomach, hip, or buttock. Do not apply a patch to the same skin twice within one week.
Try to change your Oxytrol patch on the same two days each week (such as every Sunday and Thursday). There is a calendar printed on the package of Oxytrol to help you establish a steady patch-changing schedule.
If the patch falls off, try sticking it back on. If it does not stay on, replace it with a new one and wear it until your next regular patch-changing day. Do not change your schedule, even if you apply a new Oxytrol patch to replace one that has fallen off.
After removing a patch, fold it in half so it sticks together and flush it down the toilet or place it in a waste can with a lid.
Use baby oil or mild soap and water to remove any adhesive residue that stays on your skin. Avoid using harsh soaps, alcohol, nail polish remover, or other solvents that could irritate your skin.
Keep the Oxytrol patch in its sealed pouch until you are ready to use it. Store the pouches at room temperature away from heat and moisture.
What happens if I miss a dose?
If you forget to change a patch on your scheduled day, remove and replace the Oxytrol patch as soon as you remember. Wear the patch until your next regular patch-changing day. Do not change your schedule, even if you wear the new patch for less that 3 days.
Do not apply two patches at the same time to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention if you think you have used too much of this medicine. Symptoms of an Oxytrol overdose may include restlessness, tingly feeling, fever, uneven heart rate, vomiting, and urinating less than usual or not at all.
Oxytrol side effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using Oxytrol and call your doctor at once if you have any of these serious side effects:
fever with hot, dry skin;
uneven heart rate;
pain, burning, or other difficulty when urinating; or
severe itching, burning, or blistering that does not clear up within several hours after removing the skin patch.
Continue using Oxytrol and talk to your doctor if you have any of these less serious side effects:
mild skin itching, burning, redness, or discoloration where a patch was worn;
dizziness, drowsiness, weakness;
blurred vision;
dry mouth;
warmth, tingling, or redness under your skin;
nausea, vomiting, stomach pain;
constipation or diarrhea;
dry eyes;
stuffy nose;
back pain;
feeling restless; or
sleep problems (insomnia).
Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.
What other drugs will affect Oxytrol?
Before using Oxytrol, tell your doctor if you are using any of the following drugs:
atropine (Donnatal, and others);
belladonna;
clidinium (Quarzan);
dicyclomine (Bentyl);
glycopyrrolate (Robinul);
hyoscyamine (Anaspaz, Cystospaz, Levsin, and others);
mepenzolate (Cantil);
methantheline (Provocholine);
methscopolamine (Pamine);
propantheline (Pro-Banthine);
scopolamine (Transderm-Scop);
antibiotics such as clarithromycin (Biaxin), erythromycin (E-Mycin, E.E.S., Ery-Tab, Erythrocin), itraconazole (Sporanox), or ketoconazole (Nizoral).
If you are using any of these drugs, you may not be able to use Oxytrol, or you may need dosage adjustments or special tests during treatment.
There may be other drugs not listed that can affect Oxytrol. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.
Primidone is an anti-epileptic drug, also called an anticonvulsant.
Primidone is used to control seizures.
Primidone may also be used for other purposes not listed in this medication guide.
What is the most important information I should know about Mysoline (primidone)?
You should not use this medication if you are allergic to primidone or phenobarbital (Luminal, Solfoton), or if you have porphyria.
Before taking this medication, tell your doctor if you are allergic to any drugs, or if you are pregnant or breast-feeding.
You may have thoughts about suicide while taking this medication. Your doctor will need to check you at regular visits. Do not miss any scheduled appointments.
Call your doctor at once if you have any new or worsening symptoms such as: mood or behavior changes, depression, anxiety, or if you feel agitated, hostile, restless, hyperactive (mentally or physically), or have thoughts about suicide or hurting yourself. If you are taking primidone to prevent seizures, keep taking the medication even if you feel fine. You may have an increase in seizures if you stop taking primidone. Follow your doctor’s instructions.
To be sure this medication is helping your condition, your blood may need to be tested on a regular basis. Do not miss any scheduled appointments.
Do not change your dose of primidone without your doctor’s advice. Tell your doctor if the medication does not seem to work as well in treating your condition.
Carry an ID card or wear a medical alert bracelet stating that you are taking primidone, in case of emergency. Any doctor, dentist, or emergency medical care provider who treats you should know that you are taking a seizure medication.
What should I discuss with my healthcare provider before taking Mysoline (primidone)?
You should not use this medication if you are allergic to primidone or phenobarbital (Luminal, Solfoton), or if you have porphyria.
You may have thoughts about suicide while taking this medication. Tell your doctor if you have new or worsening depression or suicidal thoughts during the first several months of treatment, or whenever your dose is changed.
Your family or other caregivers should also be alert to changes in your mood or symptoms. Your doctor will need to check you at regular visits. Do not miss any scheduled appointments.
Before taking this medication, tell your doctor if you are allergic to any drugs, or if you are pregnant or breast-feeding.
Primidone may cause harm to an unborn baby, but having a seizure during pregnancy could harm both the mother and the baby. Do not start taking primidone during pregnancy without your doctor’s advice.
If you become pregnant while taking primidone, do not stop taking it without telling your doctor. Seizure control is very important during pregnancy and the benefits of preventing seizures may outweigh any risks posed by taking primidone.
If you have taken primidone during pregnancy, be sure to tell the doctor who delivers your baby about your primidone use. Both you and the baby may need to receive medications to prevent excessive bleeding during delivery and just after birth.
Primidone can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
How should I take Mysoline (primidone)?
Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.
Primidone is usually taken 2 to 4 times daily. If you are switching to primidone from another seizure medication, you may need to start taking primidone only at bedtime. Follow your doctor’s instructions.
If you are taking primidone to treat seizures, keep taking the medication even if you feel fine. You may have an increase in seizures if you stop taking primidone. Follow your doctor’s instructions.
To be sure this medication is helping your condition, your blood may need to be tested on a regular basis. Do not miss any scheduled appointments.
Do not change your dose of primidone without your doctor’s advice. Tell your doctor if the medication does not seem to work as well in treating your condition.
Carry an ID card or wear a medical alert bracelet stating that you are taking primidone, in case of emergency. Any doctor, dentist, or emergency medical care provider who treats you should know that you are taking a seizure medication. Store primidone at room temperature away from moisture, light, and heat.
What happens if I miss a dose?
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at your next regularly scheduled time. Do not take extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention if you think you have used too much of this medicine.
Symptoms of a primidone overdose are not known.
Mysoline (primidone) side effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any new or worsening symptoms such as: mood or behavior changes, depression, anxiety, or if you feel agitated, hostile, restless, hyperactive (mentally or physically), or have thoughts about suicide or hurting yourself.
Call your doctor at once if you have any of these serious side effects:
slurred speech;
loss of balance or coordination;
easy bruising or bleeding; or
unusual weakness.
Less serious side effects may include:
dizziness, drowsiness, spinning sensation;
nausea, vomiting, loss of appetite;
feeling irritable;
blurred vision;
mild skin rash; or
impotence, loss of interest in sex.
This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect.
What other drugs will affect Mysoline (primidone)?
There may be other drugs that can interact with primidone. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.
Nevirapine is an antiviral medication that prevents human immunodeficiency virus (HIV) cells from multiplying in your body.
Nevirapine is used to treat HIV, which causes the acquired immunodeficiency syndrome (AIDS). Nevirapine is not a cure for HIV or AIDS.
Nevirapine may also be used for purposes other than those listed in this medication guide.
What is the most important information I should know about Viramune (nevirapine)?
Nevirapine can cause severe or life-threatening effects on the liver. Call your doctor at once if you have any of these liver symptoms while taking nevirapine: skin rash, nausea, stomach pain, loss of appetite, low fever, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes). Nevirapine may also cause severe or life-threatening skin reactions. Contact your doctor if you have any type of skin rash. Even a minor skin rash could be an early sign of a serious reaction. Later signs include fever, sore throat, and headache with a severe blistering, peeling, and red skin rash. This type of reaction is a medical emergency.
There are many other medicines that can interact with nevirapine, or make it less effective. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor. Keep a list with you of all the medicines you use and show this list to any doctor or other healthcare provider who treats you.
HIV/AIDS is usually treated with a combination of different drugs. To best treat your condition, use all of your medications as directed by your doctor. Do not change your doses or medication schedule without advice from your doctor. Every person with HIV or AIDS should remain under the care of a doctor.
Taking nevirapine will not prevent you from passing HIV to other people through unprotected sex or sharing of needles. Talk with your doctor about safe methods of preventing HIV transmission during sex, such as using a condom and spermicide. Sharing drug or medicine needles is never safe, even for a healthy person.
What should I discuss with my healthcare provider before taking Viramune (nevirapine)?
Nevirapine can cause severe or life-threatening effects on the liver. Call your doctor at once if you have any of these liver symptoms while taking nevirapine: skin rash, nausea, stomach pain, loss of appetite, low fever, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes). Nevirapine may also cause severe or life-threatening skin reactions. Contact your doctor if you have any type of skin rash. Even a minor skin rash could be an early sign of a serious reaction. Later signs include fever, sore throat, and headache with a severe blistering, peeling, and red skin rash. This type of reaction is a medical emergency. Do not use this medication if you are allergic to nevirapine.
Before taking nevirapine, tell your doctor if you are allergic to any drugs, or if you have:
liver disease;
kidney disease (or if you are on dialysis); or
if you have ever taken delavirdine (Rescriptor) or efavirenz (Sustiva) and they were not effective in treating your condition.
If you have any of these conditions, you may not be able to use nevirapine, or you may need a dosage adjustment or special tests during treatment.
FDA pregnancy category C. This medication may be harmful to an unborn baby. Nevirapine may also be more likely to cause liver damage in a pregnant woman. Tell your doctor if you are pregnant or plan to become pregnant during treatment. HIV can be passed to the baby if the mother is not properly treated during pregnancy. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Take all of your HIV medicines as directed to control your infection while you are pregnant. Nevirapine can make birth control pills less effective. Ask your doctor about using a non-hormone method of birth control (such as a condom, diaphragm, spermicide) to prevent pregnancy while taking nevirapine.
Your name may need to be listed on an antiviral pregnancy registry when you start using nevirapine. The purpose of this registry is to track the outcome of the pregnancy and delivery to evaluate whether nevirapine had any effect on the baby.
You should not breast-feed while you are using nevirapine. Women with HIV or AIDS should not breast-feed at all. Even if your baby is born without HIV, you may still pass the virus to the baby in your breast milk.
How should I take Viramune (nevirapine)?
Take nevirapine exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.
Nevirapine is usually taken only once daily for the first 2 weeks, and then increased to twice daily. Starting with a low dose can reduce your risk of skin reactions. Follow your doctor’s instructions about how often to take the medication.
If you stop taking nevirapine for 7 days or longer, call your doctor before you start taking the medicine again. You may have to start with a lower dose.
Take nevirapine with a full glass of water. You may also take the medicine with milk or a soft drink.
Nevirapine can be taken with or without food.
Shake the oral suspension (liquid) well just before you measure a dose. To be sure you get the correct dose, measure the liquid with a marked measuring spoon or medicine cup, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.
To be sure this medication is helping your condition, your blood cells and liver function will need to be tested on a regular basis. This testing is especially important during the first 6 to 18 weeks you are taking nevirapine. Do not miss any scheduled visits to your doctor.
It is important to take nevirapine regularly to get the most benefit. Get your prescriptions refilled before you run out of medicine completely.
Do not take nevirapine as your only HIV medication. HIV/AIDS is usually treated with a combination of different drugs. Your disease may become resistant to nevirapine if you do not take it in combination with other HIV medicines your doctor has prescribed.
To best treat your condition, use all of your medications as directed by your doctor. Do not change your doses or medication schedule without advice from your doctor. Every person with HIV or AIDS should remain under the care of a doctor.
Store nevirapine at room temperature away from moisture and heat.
What happens if I miss a dose?
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention if you think you have used too much of this medicine.
Symptoms of a nevirapine overdose may include skin rash, headache, dizziness, tired feeling, sleep problems, nausea, vomiting , weight loss, joint pain or swelling, red or tender bumps on your shins, wheezing, cough, or trouble breathing.
Viramune (nevirapine) side effects
Get emergency medical help if you have any of these signs of an allergic reaction: tired feeling, joint or muscle pain, muscle weakness, skin rash, bruising, severe tingling, numbness, mouth sores, trouble breathing, or swelling of your face, lips, tongue, or throat. Stop taking nevirapine and call your doctor at once if you have:
fever, sore throat, and headache with a severe blistering, peeling, and red skin rash;
nausea, stomach pain, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
fever, chills, body aches, flu symptoms; or
any other signs of new infection.
Keep taking nevirapine if you have any of these less serious side effects:
nausea, vomiting, stomach pain;
headache, tired feeling; or
changes in body fat (e.g., increased fat in the upper back, neck, breast, and trunk and loss of fat from the legs, arms, and face).
Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.
What other drugs will affect Viramune (nevirapine)?
There are many other medicines that can interact with nevirapine, or make it less effective. Before taking nevirapine, tell your doctor if you are using any of the following drugs:
St. John’s wort;
a blood thinner such as warfarin (Coumadin);
an antibiotic such as clarithromycin (Biaxin), itraconazole (Sporanox), rifabutin (Mycobutin), or rifampin (Rifadin, Rifater, Rifamate, Rimactane);
ergot medicine such as ergotamine (Ergomar, Ergostat, Cafergot, Ercaf, Wigraine), dihydroergotamine (D.H.E. 45, Migranal Nasal Spray), ergonovine (Ergotrate), or methylergonovine (Methergine);
heart or blood pressure medications such as amlodipine (Norvasc), diltiazem (Tiazac, Cartia, Cardizem), felodipine (Plendil), nicardipine (Cardene), nifedipine (Procardia, Adalat), nimodipine (Nimotop), nisoldipine (Sular), or verapamil (Calan, Covera, Isoptin, Verelan);
medication to prevent organ transplant rejection;
other HIV medicines such as nelfinavir (Viracept), efavirenz (Sustiva), indinavir (Crixivan), lopinovir/ritonavir (Kaletra), nevirapine (Viramune), or saquinavir (Invirase); or
seizure medications such as carbamazepine (Tegretol), clonazepam (Klonipin), or ethosuximide (Zarontin).
If you are using any of these drugs, you may not be able to use nevirapine, or you may need dosage adjustments or special tests during treatment.
Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor. Keep a list with you of all the medicines you use and show this list to any doctor or other healthcare provider who treats you.
Chlorambucil is a cancer medication that interferes with cancer cells and slows their growth and spread in the body.
Chlorambucil is used to treat several types of cancer, including Hodgkin’s disease and certain types of leukemia or lymphoma.
Chlorambucil may also be used for purposes other than those listed in this medication guide.
What is the most important information I should know about Leukeran (chlorambucil)?
Do not use this medication without telling your doctor if you are pregnant. It could cause harm to the unborn baby. Use an effective form of birth control, and tell your doctor if you become pregnant during treatment.
Treatment with chlorambucil may increase your risk of developing other forms of cancer. This medication can also affect fertility (your ability to have children), whether you are a man or a woman. Talk to your doctor about your specific risks when using chlorambucil.
Chlorambucil can lower the blood cells that help your body fight infections. This can make it easier for you to bleed from an injury or get sick from being around others who are ill. To be sure your blood cells do not get too low, your blood will need to be tested on a regular basis. Do not miss any scheduled visits to your doctor.
Do not receive a “live” vaccine while you are being treated with chlorambucil.
Stop using chlorambucil and call your doctor at once if you have a seizure, red or peeling skin rash, severe nausea or stomach pain, jaundice (yellowing of your skin or eyes), any unusual mass or lump, fever, chills, sore throat, cough, flu-like symptoms, pale skin, easy bruising or bleeding, unusual weakness, white patches or sores inside your mouth or on your lips, or missed menstrual periods.
What should I discuss with my healthcare provider before taking Leukeran (chlorambucil)?
Do not use this medication if you are allergic to chlorambucil, or if you have received this medication in the past without successful treatment of your condition.
Before using chlorambucil, tell your doctor if you are allergic to any drugs, or if you have received radiation treatment within the past 4 weeks. You may not be able to use chlorambucil, or you may need a dosage adjustment or special tests during treatment.
FDA pregnancy category D. This medication can cause harm to an unborn baby. Do not use chlorambucil without your doctor’s consent if you are pregnant. Tell your doctor if you become pregnant during treatment. Use an effective form of birth control while you are using this medication.
This medication can affect fertility (your ability to have children), whether you are a man or a woman.
It is not known whether chlorambucil passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
Treatment with chlorambucil may increase your risk of developing other forms of cancer. Talk to your doctor about your specific risk.
How should I take Leukeran (chlorambucil)?
Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label. You should not take chlorambucil unless you remain under the care of a doctor.
Take this medicine with a full glass of water.
Chlorambucil can lower the blood cells that help your body fight infections. This can make it easier for you to bleed from an injury or get sick from being around others who are ill. To be sure your blood cells do not get too low, your blood will need to be tested on a regular basis. Do not miss any scheduled visits to your doctor.
Store chlorambucil in the refrigerator but do not allow it to freeze.
What happens if I miss a dose?
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at your next regularly scheduled time. Do not take extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention if you think you have used too much of this medicine.
Symptoms of a chlorambucil overdose may include agitation, loss of balance or coordination, or seizure (convulsions).
Leukeran (chlorambucil) side effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using chlorambucil and call your doctor at once if you have any of these serious side effects:
seizure (convulsions);
fever, sore throat, and headache with a severe blistering, peeling, and red skin rash;
nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
an unusual mass or lump;
fever, chills, body aches, flu symptoms, or ongoing cough;
pale skin, easy bruising or bleeding, unusual weakness;
white patches or sores inside your mouth or on your lips;
severe nausea, vomiting, or diarrhea; or
missed menstrual periods.
Keep taking chlorambucil and talk to your doctor if you have any of these less serious side effects:
upset stomach, mild nausea, diarrhea;
tremors or shaking; or
numbness or tingling.
Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems or unusual or that is especially bothersome.
What other drugs will affect Leukeran (chlorambucil)?
There may be other drugs that can affect chlorambucil. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.
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